SynthesisCardiovascular and interventional radiology2023
Cryoablation for the Palliation of Painful Bone Metastasis: A Systematic Review.
Synthesis in Cardiovascular and interventional radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Survival outcomes and quality of life after percutaneous cryoablation for liver metastasis: A systematic review and meta-analysis.PloS one · 2023Pooled it
- Intra-osseous Ice Ball Visualization During Cryoablation Using Photon-Counting Detector Computed Tomography: An In-Vivo Swine Pilot Study.Cardiovascular and interventional radiology · 2026Article
- Co-Ablation System for Pain Management in Bone Metastases: Retrospective Exploratory Study.JMIR cancer · 2026Article
- A 27-Year-Old Man with Chronic Traumatic Pancreatic Fistula Managed with Percutaneous Microwave Ablation.The American journal of case reports · 2025Article
- Percutaneous microwave ablation of bone lesions: a retrospective cohort study.Insights into imaging · 2025Article
- Interventional Radiology Management of Bone Metastasis Pain: Strategies and Techniques.Cardiovascular and interventional radiology · 2025Review
- Interventional Radiology Meets Pain Management: Cutting-Edge Techniques for Lasting Relief.Cardiovascular and interventional radiology · 2025Article
- Comparing the efficacy and safety of cryoablation and microwave ablation in treating paravertebral metastases of rabbit VX2 tumor.Scientific reports · 2025Article
- Image-Guided Musculoskeletal Interventional Radiology in the Personalised Management of Musculoskeletal Tumours.Journal of personalized medicine · 2024Review
- Application of combined ablation and immunotherapy in NSCLC and liver cancer: Current status and future prospects.Heliyon · 2024Review
- The New Ice Age of Musculoskeletal Intervention: Role of Percutaneous Cryoablation in Bone and Soft Tissue Tumors.Current oncology (Toronto, Ont.) · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCryoablation is a minimally invasive procedure to treat painful bone metastases in patients with cancer. We designed a systematic review to understand the safety and effects of cryoablation on the pain and quality of life (QoL) of cancer patients.
methodWe searched PubMed, ISI, Cochrane library, and Scopus databases using the keywords "Cryoablation," "Pain," and "Bone metastasis." Inclusion criteria were: (1) Original studies published until September 8, 2022; (2) studies on patients over 18 years and affected by bone metastasis; (3) bone metastasis treated with stand-alone cryoablation; (4) studies reporting patients' pain before and at least one time-point following cryoablation; and (5) English-language studies.
resultsWe screened 696 articles. Fifteen studies on 376 patients were included. Time points for pain assessment ranged from 1 day to 6 months. Spine was the most frequent treated location. All studies reported a significant pain reduction between 1 day and 6 months after the cryoablation procedure. The highest mean difference between pre- and post-procedure scores was 5.8 (VAS scale) after 4 weeks. The overall rate of minor and major complications was 12.74%. Cryoablation improved the QoL of cancer patients and decreased the need for analgesics.
conclusionCryoablation is a safe and useful procedure for palliating painful bone metastasis and increasing the QoL of cancer patients. Future studies should adopt a standardized pain reporting scale to allow for meta-analysis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.