SynthesisScientific reports2023
Effects of monensin supplementation on lactation performance of dairy cows: a systematic review and dose-response meta‑analysis.
Synthesis in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 18 citations in OpenAlex.
- Effects of Sodium Monensin and a Tannin-Yeast Blend on Intake, Milk Yield, and Methane Emissions in Lactating Holstein Cows.Animals : an open access journal from MDPI · 2026Article
- Green propolis extract replaces salinomycin in the high-concentrate diet of sheep.Tropical animal health and production · 2026Article
- Monensin reduces enteric methane emissions in late-lactation Holstein cows fed high-concentrate diets.JDS communications · 2026Article
- Critical Analysis of Protocols for Good Veterinary Practices in Monitoring, Prevention and Treatment of Ketosis in Dairy Cows.Veterinary sciences · 2025Review
- Phytochemicals and Monensin in Dairy Cows: Impact on Productive Performance and Ruminal Fermentation Profile.Animals : an open access journal from MDPI · 2025Article
- Mitigating enteric methane emissions: An overview of methanogenesis, inhibitors and future prospects.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2025Review
- Effects of monensin, phytogenic compounds, or a blend of feed additives on health and performance of dairy cows.Translational animal science · 2025Article
- Dynamic insights into mitochondrial function: Monitoring viscosity and SOJournal of photochemistry and photobiology. B, Biology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to conduct a comprehensive review with meta-analysis to determine the effects of the dose-response relationship between monensin supplementation and dairy cow performance and milk composition. Results from 566 full-text articles and 48 articles with 52 studies were meta-analyzed for pooled estimates. Monensin supplementation up to 23 ppm increased milk production, with the optimal dose being 12.6 ppm. Monensin supplementation at doses ranging from 16 to 96 ppm increased milk production in the prepartum phase (- 28 to 0 day relative to calving). From 60 to 150 DIM, monensin supplementation up to 21 ppm had a significant positive effect on this outcome, while supplementation in the 37 to 96 ppm range caused a decrease in this variable. At 0 to 60 and > 150 DIM, monensin supplementation had no effect on milk yield. At dosages of 22 to 96 ppm, 12 to 36 ppm, and below 58 ppm and 35 ppm, respectively, monensin supplementation resulted in significant decreases in dry matter intake (DMI), milk protein percentage, milk fat percentage, and milk fat yield. Overall, based on the results of this meta-analysis and considering all variables, the recommended optimal dose of monensin could be about 16 ppm.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.