SynthesisScientific reports2023
Nitrate contamination in drinking water and adverse reproductive and birth outcomes: a systematic review and meta-analysis.
Synthesis in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Exposure to drinking water pollutants and non-syndromic birth defects: a systematic review and meta-analysis synthesis.BMJ open · 2024Pooled it
- Review
- Integrated nitrate bioremediation and microbial risk mitigation using Bacillus pacificus.Biodegradation · 2026Article
- Serum NO₃⁻ and NO₂⁻ levels among pregnant women from agricultural communities: associations with self-reported dietary and environmental exposures.Scientific reports · 2026Article
- Ammonium and nitrate fluxes drive metabolic functional shifts in tap water biofilms.Applied microbiology and biotechnology · 2026Article
- Efficacy and limitations of the A2O process in simultaneous removal of surfactants and nutrients from municipal wastewater.Scientific reports · 2026Article
- Public drinking water contaminant estimates for birth cohorts in the Environmental Influences on Child Health Outcomes (ECHO) Cohort.Journal of exposure science & environmental epidemiology · 2026Article
- One Health, One Planet: rethinking public health in the era of pesticides, fertilizers, and antibiotics.Frontiers in public health · 2026Article
- Article
- A Review of the Evidence of the Toxicity of Chemical Substances Included in the European Union Ambient Air Quality and Drinking Water Directives: Perspectives for Health Impact Assessments.Environment & health (Washington, D.C.) · 2025Review
- Mapping drinking water contamination in Gazipur City restaurants using WQI and multivariate analysis.Water science and technology : a journal of the International Association on Water Pollution Research · 2025Article
- Efficiency, Microbial Communities, and Nitrogen Metabolism in Denitrification Biological Filter: Insights into Varied Pore Ceramsite Media.Microorganisms · 2025Article
- A two-stage model of the fuzzy analytic hierarchy process and the fuzzy synthetic evaluation technique to prioritize sustainable sanitation services under uncertainty.Scientific reports · 2025Article
- Role of Structural and Compositional Changes of CuACS applied energy materials · 2024Article
- Direct potable reuse and birth defects prevalence in Texas: An augmented synthetic control method analysis of data from a population-based birth defects registry.Environmental epidemiology (Philadelphia, Pa.) · 2024Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Exposure to low levels of nitrate in drinking water may have adverse reproductive effects. We reviewed evidence about the association between nitrate in drinking water and adverse reproductive outcomes published to November 2022. Randomized trials, cohort or case-control studies published in English that reported the relationship between nitrate intake from drinking water and the risk of perinatal outcomes were included. Random-effect models were used to pool data. Three cohort studies showed nitrate in drinking water is associated with an increased risk of preterm birth (odds ratio for 1 mg/L NO
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.