Evidence map›Paper›PMID 36631487›Full record

ArticleNature communications2023

TGFβ1

Jinbo Li, Zhenqiang Yao, Xin Liu, Rong Duan, Xiangjiao Yi, Akram Ayoub, James O Sanders, Addisu Mesfin, Lianping Xing, Brendan F Boyce

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. A RANKLBone research · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Jinbo LiDepartment of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY, 14642, USA. Jinbo_Li@hebmu.edu.cn.ORCID 0000-0003-1565-4173
Zhenqiang YaoDepartment of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY, 14642, USA.ORCID 0000-0002-4664-3648
Xin LiuDepartment of Orthopedics, Tianjin Hospital, Tianjin, China.
Rong DuanDepartment of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY, 14642, USA.
Xiangjiao YiThe First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, Anhui, China.
Akram AyoubDepartment of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY, 14642, USA.
James O SandersDepartment of Orthopaedics and Rehabilitation Medicine, University of Rochester Medical Center, Rochester, NY, 14642, USA.ORCID 0000-0001-7897-4161
Addisu MesfinDepartment of Orthopaedics and Rehabilitation Medicine, University of Rochester Medical Center, Rochester, NY, 14642, USA.ORCID 0000-0003-0076-4185
Lianping XingDepartment of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY, 14642, USA.ORCID 0000-0002-2588-7766
Brendan F BoyceDepartment of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY, 14642, USA. brendan_boyce@urmc.rochester.edu.ORCID 0000-0002-3587-4854
University of Rochester Medical Center · USAnhui University of Traditional Chinese Medicine · CNHebei Medical University · CNTianjin Hospital · CNUniversity of North Carolina at Chapel Hill · US

Funding

Studies on the fate of the OsteoclastR01AR043510 · NIAMS · UNIVERSITY OF TEXAS HLTH SCI CTR SAN ANT · PI BOYCE, BRENDAN F · 1995 to 2025
$8.4M
Rochester Resource-Based Center for Bone, Muscle and Orthopaedic Research (ROCSTARR) (Overall Application)P30AR069655 · NIAMS · UNIVERSITY OF ROCHESTER · PI Edward M. Schwarz · 2016 to 2026
$7.8M
Role of Macrophage in Osteoimmunology with AgingR01AG076731 · NIA · UNIVERSITY OF ROCHESTER · PI Zhenqiang Yao · 2022 to 2026
$2.1M
Synovial lymphatics and osteoarthritis in agingR01AG059775 · NIA · UNIVERSITY OF ROCHESTER · PI XING, LIANPING · 2020 to 2024
$1.9M
Studies of TRAF3 in age-related low-level chronic inflammation and osteoporosisR01AG049994 · NIA · UNIVERSITY OF ROCHESTER · PI BOYCE, BRENDAN F, YAO, ZHENQIANG · 2016 to 2020
$1.6M
Study of osteoblast regulation in TNF-mediated bone lossR01AR063650 · NIAMS · UNIVERSITY OF ROCHESTER · PI XING, LIANPING · 2013 to 2016
$1.4M
Olympus NanoZoomer RS Whole Slide Imaging SystemS10RR027340 · NCRR · UNIVERSITY OF ROCHESTER · PI BOYCE, BRENDAN F · 2010 to 2010
$340k
NCRR NIH HHS S10 RR027340NIAMS NIH HHS P30 AR069655NIAMS NIH HHS R01 AR043510NIAMS NIH HHS R01 AR063650NIA NIH HHS R01 AG049994NIA NIH HHS R01 AG059775NIA NIH HHS R01 AG076731
6 · The paper itself

Abstract

TGFβ1 induces age-related bone loss by promoting degradation of TNF receptor-associated factor 3 (TRAF3), levels of which decrease in murine and human bone during aging. We report that a subset of neutrophils (TGFβ1

Indexed as

Bone MarrowNeutrophilsOsteoporosisAnimalsMaleMaravirocMiceReceptors, CCR5TNF Receptor-Associated Factor 3Transforming Growth Factor betaMaravirocReceptors, CCR5TNF Receptor-Associated Factor 3Transforming Growth Factor beta

Identifiers

PMID36631487
PMCPMC9834218
OpenAlexW4315646548

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.