Trial reportCell reports. Medicine2023
Brief structured respiration practices enhance mood and reduce physiological arousal.
Trial report in Cell reports. Medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 7 registered trials, which are not on this map. Cited by 112 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Psychophysiological Effects of Controlled Respiration: Noninvasive Relaxation Techniques
The Effectiveness of Lavender Aromatherapy Combined With Slow Breathing Exercises in Improving Occupational Burnout and Sleep Disorders Among Nursing Staff
Effects of Paced Breathing Versus Diaphragmatic Breathing Combined With Mat Pilates on Cardiopulmonary Endurance, Dyspnea, Stress, Anxiety, and Quality of Life in Patients With Stage II Hypertension: A Randomized Controlled Trial
A Box Breathing Intervention and the Surgical Stress Response in Older Adults Undergoing Total Knee Arthroplasty: A Randomized Controlled Feasibility Trial
The Acute Effects of Controlled Breathing Exercises and Music Therapy on the Autonomic Nervous System in Anxious Individuals: A Randomized Controlled Study
Effect of Brief Breathwork and Mindfulness Interventions on Anxiety, Psychological Flexibility and Physiological Variables in Spanish-Speaking University Students: a Four-Arm Randomized Controlled Trial
Effect of Box Breathing Exercise on Anxiety, Pain, and Pulmonary Function Tests in Patients Undergoing Colonoscopy: Randomized Controlled Trial
Who cites it
112 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Virtual Reality Breathing Interventions for Mental Health: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Applied psychophysiology and biofeedback · 2024Pooled it
- A systematic review of brief respiratory, embodiment, cognitive, and mindfulness interventions to reduce state anxiety.Frontiers in psychology · 2024Pooled it
- Time course of perceptual, cognitive, physical and physiological responses to a single non-sleep deep rest session in physically active young adults.Applied psychology. Health and well-being · 2026Trial
- Clinical effectiveness of diaphragmatic breathing for dental anxiety in 7- to 13-year-old children.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Trial
- Effect of virtual reality on pain and anxiety during colonoscopy: A randomized control trial.The Journal of international medical research · 2026Trial
- Focused Attention Meditation as a Pre-Exercise Strategy for Reducing Anxiety in Speed Skaters.Sensors (Basel, Switzerland) · 2026Trial
- A semi-randomised control trial assessing psychophysiological effects of breathwork and cold immersion.Scientific reports · 2025Trial
- Effects of mindfulness breathing meditation on stress and cognitive functions: a heart rate variability and eye-tracking study.Scientific reports · 2025Trial
- Effectiveness of Finnish SISU training in enhancing prehospital personnels' work performance: A randomised controlled pilot study.BMC emergency medicine · 2025Trial
- A 14-week structured breathing program: an investigation into its impact on psychological health parameters in university students.BMC public health · 2025Trial
- The Selah trial: A preference-based partially randomized waitlist control study of three stress management interventions.Translational behavioral medicine · 2025Trial
- Breathing therapy for patients with medically unexplained physical symptoms and dysfunctional breathing: A pilot and feasibility trial.PloS one · 2025Trial
- Box breathing or six breaths per minute: Which strategy improves athletes post-HIIT cardiovascular recovery?PloS one · 2025Trial
- Vagally Mediated Heart Rate Variability and Mood States in Patients with Chronic Pain Receiving Prolonged Expiration Regulated Breathing: A Randomized Controlled Trial.Applied psychophysiology and biofeedback · 2024Trial
- Lightening the mind with audiovisual stimulation as an accessible alternative to breath-focused meditation for mood and cognitive enhancement.Scientific reports · 2024Trial
- Effects of brief remote high ventilation breathwork with retention on mental health and wellbeing: a randomised placebo-controlled trial.Scientific reports · 2024Trial
- Stress reduction experiments in daily life: Scaling from the lab to the world.Journal of experimental psychology. General · 2024Trial
- Trial
- Effect of coherent breathing on mental health and wellbeing: a randomised placebo-controlled trial.Scientific reports · 2023Trial
- The effect of brief exposure to virtual nature on mental wellbeing in adolescents.Scientific reports · 2023Trial
52 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
Controlled breathwork practices have emerged as potential tools for stress management and well-being. Here, we report a remote, randomized, controlled study (NCT05304000) of three different daily 5-min breathwork exercises compared with an equivalent period of mindfulness meditation over 1 month. The breathing conditions are (1) cyclic sighing, which emphasizes prolonged exhalations; (2) box breathing, which is equal duration of inhalations, breath retentions, and exhalations; and (3) cyclic hyperventilation with retention, with longer inhalations and shorter exhalations. The primary endpoints are improvement in mood and anxiety as well as reduced physiological arousal (respiratory rate, heart rate, and heart rate variability). Using a mixed-effects model, we show that breathwork, especially the exhale-focused cyclic sighing, produces greater improvement in mood (p < 0.05) and reduction in respiratory rate (p < 0.05) compared with mindfulness meditation. Daily 5-min cyclic sighing has promise as an effective stress management exercise.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.