Evidence map›Paper›PMID 36630688›Full record

ArticleACS biomaterials science & engineering2023

Fibrin-Enriched Cardiac Extracellular Matrix Hydrogel Promotes

Rubia Shaik, Jiazhu Xu, Yong Wang, Yi Hong, Ge Zhang

Open access · greenAbstract read
In one paragraph

Article in ACS biomaterials science & engineering, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
8.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 28 citations in OpenAlex.

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  11. Use of Hydrogels in Regenerative Medicine: Focus on Mechanical Properties.International journal of molecular sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Rubia ShaikDepartment of Biomedical Engineering, The University of Akron, Akron, Ohio 44325, United States.
Jiazhu XuDepartment of Bioengineering, University of Texas at Arlington, Arlington, Texas 76019, United States.
Yong WangDepartment of Biomedical Engineering, Pennsylvania State University, State College, University Park, Pennsylvania 16801, United States.ORCID 0000-0002-2244-1742
Yi HongDepartment of Bioengineering, University of Texas at Arlington, Arlington, Texas 76019, United States.ORCID 0000-0002-5846-2596
Ge ZhangDepartment of Biomedical Engineering, The University of Akron, Akron, Ohio 44325, United States.ORCID 0000-0001-8339-1892
The University of Texas at Arlington · USUniversity of Akron · USPennsylvania State University · US

Funding

Molecularly regulated release of angiogenic factors from superporous hydrogelsR01HL122311 · NHLBI · PENNSYLVANIA STATE UNIVERSITY, THE · PI WANG, YONG · 2015 to 2023
$4.2M
Bioactive injectable blends for cardiac stem cell recruitmentR15HL140503 · NHLBI · UNIVERSITY OF TEXAS ARLINGTON · PI HONG, YI · 2018 to 2018
$460k
Maturation Strategies for Engineered Human Cardiac MicrotissuesR15HL172207 · NHLBI · UNIVERSITY OF AKRON · PI ZHANG, GE · 2024 to 2024
$448k
NHLBI NIH HHS R01 HL122311NHLBI NIH HHS R15 HL140503NHLBI NIH HHS R15 HL172207
6 · The paper itself

Abstract

Angiogenesis is essential for cardiac repair after myocardial infarction. Promoting angiogenesis has been demonstrated as an effective approach for myocardial infarction treatment. Several different strategies for inducing myocardial angiogenesis have been explored, including exogenous delivery of angiogenic genes, proteins, microRNAs, cells, and extracellular vesicles. Various types of injectable hydrogels have been investigated for cardiac tissue repair. One of the most promising injectable hydrogels in cardiac regeneration is a cardiac extracellular matrix hydrogel that is derived from decellularized porcine myocardium. It can be delivered minimally invasively

Indexed as

Extracellular MatrixFibrinHuman Umbilical Vein Endothelial CellsHydrogelsMyocardial InfarctionAnimalsHeartHumansNeovascularization, PhysiologicSwineFibrinHydrogelsangiogenesis assaycardiac extracellular matrixfibrinhuman umbilical vein endothelial cellsinjectable hydrogelmesenchymal stem cells

Identifiers

PMID36630688
PMCPMC10064974
OpenAlexW4315631830

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.