Evidence map›Paper›PMID 36630498›Full record

ArticleScience advances2023

A dual organelle-targeting mechanosensitive probe.

Po-Yu Ho, Tsu Yu Chou, Chuen Kam, Wenbin Huang, Zikai He, Alfonso H W Ngan, Sijie Chen

Abstract read
In one paragraph

Article in Science advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Coacervate-Mediated Lysosome-Targeting Antibody Delivery for Protein Degradation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Review
  3. Article
  4. FluorogenicJACS Au · 2023
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Po-Yu HoMing Wai Lau Centre for Reparative Medicine, Karolinska Institutet, Hong Kong, P. R. China.ORCID 0000-0002-2543-9541
Tsu Yu ChouMing Wai Lau Centre for Reparative Medicine, Karolinska Institutet, Hong Kong, P. R. China.ORCID 0000-0002-5891-7749
Chuen KamMing Wai Lau Centre for Reparative Medicine, Karolinska Institutet, Hong Kong, P. R. China.ORCID 0000-0001-8913-167X
Wenbin HuangSchool of Science, Harbin Institute of Technology, Shenzhen, HIT Campus of University Town, Shenzhen 518055, P. R. China.ORCID 0000-0003-3962-1114
Zikai HeSchool of Science, Harbin Institute of Technology, Shenzhen, HIT Campus of University Town, Shenzhen 518055, P. R. China.ORCID 0000-0001-9943-5677
Alfonso H W NganDepartment of Mechanical Engineering, The University of Hong Kong, Pokfulam Road, Hong Kong, P. R. China.ORCID 0000-0002-9299-1504
Sijie ChenMing Wai Lau Centre for Reparative Medicine, Karolinska Institutet, Hong Kong, P. R. China.ORCID 0000-0001-5263-9189

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cells are responsive to the mechanical environment, but the methods to detect simultaneously how different organelles react in mechanobiological processes remain largely unexplored. We herein report a dual organelle-targeting fluorescent probe, (

Identifiers

PMID36630498
PMCPMC9833668

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.