Evidence map›Paper›PMID 36629937›Full record

ArticleRheumatology international2023

Incidence of seropositive rheumatoid arthritis in population-based studies in Northern Savo, Finland, during 1980-2020.

Pia Elfving, Aulikki Kononoff, Johanna Huhtakangas, Hannu Kautiainen, Elina Savolainen, Leena Arstila, Julia Barantseva, Tuomas Rannio, Helena Niinisalo, Antti Puolitaival and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Rheumatology international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Pia ElfvingDepartment of Medicine, Kuopio University Hospital, PO. Box 100, 70029 KYS, Kuopio, Finland.ORCID 0000-0002-9885-7242
Aulikki KononoffDepartment of Medicine, Kuopio University Hospital, PO. Box 100, 70029 KYS, Kuopio, Finland.ORCID 0000-0002-0211-9238
Johanna HuhtakangasDepartment of Medicine, Kuopio University Hospital, PO. Box 100, 70029 KYS, Kuopio, Finland.ORCID 0000-0002-2090-3173
Hannu KautiainenDepartment of Public Health, Kuopio University Hospital, Kuopio, Finland.ORCID 0000-0003-0786-0858
Elina SavolainenDepartment of Medicine, Kuopio University Hospital, PO. Box 100, 70029 KYS, Kuopio, Finland.ORCID 0000-0002-3796-5143
Leena ArstilaIisalmi Hospital, Iisalmi, Finland.ORCID 0000-0002-4956-4398
Julia BarantsevaDepartment of Medicine, Kuopio University Hospital, PO. Box 100, 70029 KYS, Kuopio, Finland.ORCID 0000-0002-9695-8971
Tuomas RannioIisalmi Hospital, Iisalmi, Finland.ORCID 0000-0002-2418-687X
Helena NiinisaloDepartment of Medicine, Kuopio University Hospital, PO. Box 100, 70029 KYS, Kuopio, Finland.ORCID 0000-0002-3321-5345
Antti PuolitaivalTerveystalo, Kuopio, Finland.ORCID 0000-0002-0739-6509
Kati SoininenDepartment of Medicine, Kuopio University Hospital, PO. Box 100, 70029 KYS, Kuopio, Finland.ORCID 0000-0002-5072-1231
Simo KariniemiDepartment of Medicine, Kuopio University Hospital, PO. Box 100, 70029 KYS, Kuopio, Finland.ORCID 0000-0001-8355-0531
Minni OksarantaDepartment of Medicine, Kuopio University Hospital, PO. Box 100, 70029 KYS, Kuopio, Finland.ORCID 0000-0001-8849-0128
Oili Kaipiainen-SeppänenDepartment of Medicine, Kuopio University Hospital, PO. Box 100, 70029 KYS, Kuopio, Finland. oili.kaipiainen-seppanen@kuh.fi.ORCID 0000-0001-5650-2788
Kuopio University Hospital · FIEtelä-Karjalan sosiaali ja terveyspiiri · FIUniversity of Eastern Finland · FIMega Electronics (Finland) · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective is to evaluate the incidence of seropositive rheumatoid arthritis (RA) over 40-year period in Northern Savo, Finland. Data on new seropositive RA patients according to the American College of Rheumatology (ACR) 1987 classification criteria were collected in 2020-2021. In 2020 data on tobacco exposure, patient-reported dental health and living in residences with fluoridated tap water were gathered. Incidence rates were estimated and age- and gender-adjusted to Northern Savo population. The results were compared with data acquired in studies from 1980, 1990, 2000, and 2010. In 2020, 46 seropositive RA patients (21 females and 25 males) were recorded. The crude incidence of seropositive RA fulfilling the ACR 87 criteria in 2020 was 22.3 (95% CI 16.3 to 29.8)/100 000 and age and gender-adjusted 22.3 (95% CI 15.9 to 28.8)/100 000. Tobacco exposure > 5 pack years occurred 18% of females and 56% of males. Only 16% of males were full dentate. A total of 242 incident seropositive RA (age ≥ 16 years, 55% females) were identified in all study years. No differences in the gender-specific incidence rates in each cohort or in incidence between the studies every 10 years were recorded. The incidence of seropositive RA decreased in the age group < 55 years, p = 0.003. There was no change in the incidence of seropositive RA between genders or the study years. A declining trend for occurrence of seropositive RA in the young and early middle-aged population may reflect change in risk factors.

Indexed as

Arthritis, RheumatoidAdolescentFemaleFinlandHumansIncidenceMaleMiddle AgedRisk FactorsEpidemiologyIncidencePublic healthSeropositive rheumatoid arthritis

Identifiers

PMID36629937
PMCPMC9833634
OpenAlexW4315620034

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.