SynthesisJournal of cancer research and clinical oncology2023
Costs and clinical benefits of enhanced recovery after surgery (ERAS) in pancreaticoduodenectomy: an updated systematic review and meta-analysis.
Synthesis in Journal of cancer research and clinical oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Association Between Intraoperative Oliguria and Postoperative Acute Kidney Injury in Patients Undergoing Hepatobiliary and Pancreatic Surgery Within an Enhanced Recovery After Surgery Protocol: A Retrospective Cohort Study.Journal of clinical medicine · 2026Article
- Enhanced Recovery After Surgery in Cytoreductive Surgery With HIPEC: Implementation and Outcomes From a High-Volume Tertiary Centre in a Lower-Middle Income Country.Journal of surgical oncology · 2026Article
- A multidisciplinary comfort-enhanced recovery after surgery program improves perioperative patient-reported outcomes after lung cancer surgery: a randomized controlled trial.Journal of thoracic disease · 2026Article
- Perioperative management of pancreaticoduodenectomy for pancreatic ductal adenocarcinoma in a patient with moyamoya disease: a rare case report.Frontiers in oncology · 2026Article
- Review
- Enhanced recovery after surgery in gastric cancer surgery: Systematic review and meta-analysis of perioperative indwelling drainage tube use.World journal of gastrointestinal surgery · 2025Article
- Cost Analysis for Minimally Invasive Mitral Valve Surgery: A Single-Centre Canadian Study.CJC open · 2025Article
- Clinical application of 4N-enhanced recovery after surgery in retroperitoneal laparoscopic resection of adrenal tumors.Translational andrology and urology · 2025Article
- An institutional analysis of hospital readmission following a robotic pancreaticoduodenectomy.Journal of robotic surgery · 2024Article
- Enhanced recovery after surgery: Progress in adapted pathways for implementation in standard and emerging surgical settings.World journal of clinical cases · 2024Article
- A retrospective cohort study on enhanced recovery after surgery (ERAS) in patients with diabetic foot ulcer.Scientific reports · 2024Article
- ASO Author Reflections: One Size Does Not Fit All-Enhanced Recovery After Surgery in CRS-HIPEC.Annals of surgical oncology · 2024Article
- Adoption of an Enhanced Recovery After Surgery Protocol Increases Cost of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy and Does not Improve Outcomes.Annals of surgical oncology · 2024Article
- Intraoperative fluid management is not predictive of AKI in major pancreatic surgery: a retrospective cohort study.Journal of anesthesia, analgesia and critical care · 2024Article
- Association between delayed ambulation and increased risk of adverse events after lumbar fusion surgery in elderly patients.BMC musculoskeletal disorders · 2024Article
- Enhanced recovery after surgery may mitigate the risks associated with robotic-assisted fundoplication in lung transplant patients.Surgical endoscopy · 2024Article
- Cost-consequence analysis of the enhanced recovery after surgery protocol in major lung resection with minimally invasive technique (VATS).Frontiers in surgery · 2024Article
- Laparoscopic Pancreatoduodenectomy: Twenty years later, where are we?Revista do Colegio Brasileiro de Cirurgioes · 2024Article
- The EUPEMEN (EUropean PErioperative MEdical Networking) Protocol for Bowel Obstruction: Recommendations for Perioperative Care.Journal of clinical medicine · 2023Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
purposeERAS is a holistic and multidisciplinary pathway that incorporates various evidence-based interventions to accelerate recovery and improve clinical outcomes. However, evidence on cost benefit of ERAS in pancreaticoduodenectomy remains scarce. This review aimed to investigate cost benefit, compliance, and clinical benefits of ERAS in pancreaticoduodenectomy.
methodsA comprehensive literature search was conducted on Medline, Embase, PubMed, CINAHL and the Cochrane library to identify studies conducted between 2000 and 2021, comparing effect of ERAS programmes and traditional care on hospital cost, length of stay (LOS), complications, delayed gastric emptying (DGE), readmission, reoperation, mortality, and compliance.
resultsThe search yielded 3 RCTs and 28 cohort studies. Hospital costs were significantly reduced in the ERAS group (SMD = - 1.41; CL, - 2.05 to - 0.77; P < 0.00001). LOS was shortened by 3.15 days (MD = - 3.15; CI, - 3.94 to - 2.36; P < 0.00001) in the ERAS group. Fewer patients in the ERAS group had complications (RR = 0.83; CI, 0.76-0.91; P < 0.0001). Incidences of DGE significantly decreased in the ERAS group (RR = 0.72; CI, 0.55-0.94; P = 0.01). The number of deaths was fewer in the ERAS group (RR = 0.76; CI, 0.58-1.00; P = 0.05).
conclusionThis review demonstrated that ERAS is safe and feasible in pancreaticoduodenectomy, improves clinical outcome such as LOS, complications, DGE and mortality rates, without changing readmissions and reoperations, while delivering significant cost savings. Higher compliance is associated with better clinical outcomes, especially LOS and complications.
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