Evidence map›Paper›PMID 36629860›Full record

ArticleHealth security

Managing the Transition to Widespread Metagenomic Monitoring: Policy Considerations for Future Biosurveillance.

Chelsea Liang, James Wagstaff, Noga Aharony, Virginia Schmit, David Manheim

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Health security. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chelsea LiangChelsea Liang is an Independent Researcher, University of New South Wales, School of Biotechnology and Biomolecular Sciences, Sydney, Australia.
James WagstaffJames Wagstaff, PhD, is a Research Fellow, Future of Humanity Institute, University of Oxford, Oxford, UK.
Noga AharonyNoga Aharony, MS, is a PhD Student, Department of Systems Biology, Columbia University, New York, NY.
Virginia SchmitVirginia Schmit, PhD, is Director of Research, 1DatSooner, DE, and a Policy Specialist, National Institute of Allergy and Infectious Diseases, Bethesda, MD.
David ManheimDavid Manheim, PhD, is Head of Policy and Research, ALTER, Rehovot, Israel; Lead Researcher, 1DaySooner, Claymont, DE.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The technological possibilities and future public health importance of metagenomic sequencing have received extensive attention, but there has been little discussion about the policy and regulatory issues that need to be addressed if metagenomic sequencing is adopted as a key technology for biosurveillance. In this article, we introduce metagenomic monitoring as a possible path to eventually replacing current infectious disease monitoring models. Many key enablers are technological, whereas others are not. We therefore highlight key policy challenges and implementation questions that need to be addressed for "widespread metagenomic monitoring" to be possible. Policymakers must address pitfalls like fragmentation of the technological base, private capture of benefits, privacy concerns, the usefulness of the system during nonpandemic times, and how the future systems will enable better response. If these challenges are addressed, the technological and public health promise of metagenomic sequencing can be realized.

Indexed as

BiosurveillanceCommunicable DiseasesHealth PolicyHumansPublic HealthBiosurveillanceDisease XHealth policyMetagenomic sequencingPandemic preparednessTechnology planning

Identifiers

PMID36629860
PMCPMC9940815

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.