ArticleJournal of veterinary internal medicine2023
Autochthonous Babesia canis infections in 49 dogs in Germany.
Article in Journal of veterinary internal medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 21 citations in OpenAlex.
- Tick-borne pathogens in dogs and their ticks in France: Molecular and serological evidence from a multicenter participatory study.One health (Amsterdam, Netherlands) · 2026Article
- Treatment failure in a dog with acute Babesia canis infection using lower-range therapeutic doses of imidocarb dipropionate.Parasitology research · 2026Article
- Clinicopathological abnormalities and outcome of acuteCurrent research in parasitology & vector-borne diseases · 2026Article
- Retrospective analysis of anamnesis, clinical signs, therapy, and outcome in 342 dogs with acuteCurrent research in parasitology & vector-borne diseases · 2026Article
- Impact of levels of parasitemia and antibodies, acute-phase proteins, as well as stays abroad on hematological and biochemical parameters in 342 dogs with acute Babesia canis infection.Parasites & vectors · 2025Article
- Attachment sites of Ixodes ricinus, Ixodes hexagonus/Ixodes canisuga and Dermacentor reticulatus ticks and risk factors of infestation intensity and engorgement duration in dogs and cats.BMC veterinary research · 2025Article
- Apolipoprotein A-1 does not appear to be a suitable acute-phase reaction marker in canine babesiosis and hemoplasmosis.Current research in parasitology & vector-borne diseases · 2025Article
- Description and molecular characterisation of Babesia ailuropodae n. sp., a new piroplasmid species infecting giant pandas.Parasites & vectors · 2024Article
- Germany-wide citizen science study reveals spread ofCurrent research in parasitology & vector-borne diseases · 2024Article
- The Diverse Pathogenicity of VariousPathogens (Basel, Switzerland) · 2023Review
- Molecular detection of Babesia spp. in dogs in Germany (2007-2020) and identification of potential risk factors for infection.Parasites & vectors · 2023Article
- Autochthonous Babesia canis infections in 49 dogs in Germany.Journal of veterinary internal medicine · 2023Article
- Causes and Outcome of Systemic Inflammatory Response Syndrome in Dogs: An Observational Study of 172 Cases.Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVector-borne diseases are of increasing importance in Germany. Since 2015, autochthonous cases have been increasingly documented in Berlin/Brandenburg.
objectivesDescribe autochthonous Babesia canis infection in the Berlin/Brandenburg region. ANIMALS: Forty-nine dogs with autochthonous B. canis infection.
methodsEvaluation of history, clinical signs, laboratory abnormalities, treatment, and outcome.
resultsDogs were presented between March and August (9) and September and January (40) in the years 2015-2021. Historical and clinical findings were lethargy (100%), pale mucous membranes (63%), fever (50%), and pigmenturia (52%). Common clinicopathological findings were thrombocytopenia (100%), anemia (85%), intravascular hemolysis (52%), pancytopenia (41%), and systemic inflammatory response syndrome (SIRS; 37%). Babesia detection was based on blood smear evaluation (n = 40) and PCR targeting the 18S rRNA gene of piroplasms (n = 49). Sequencing indicated 99.47% to 100% identity to B. canis sequences from GenBank. All dogs were treated with imidocarb (2.4-6.3 mg/kg; median, 5 mg/kg); 8 dogs received 1, 35 received 2, and 1 dog each received 3, 4, or 5 injections, respectively. Continued PCR-positive results were detected in 7 dogs after the 1st, in 5 after the 2nd, in 2 after the 3rd, and in 1 28 days after the 4th injection. Four dogs were euthanized and 3 dogs died. CONCLUSIONS AND CLINICAL IMPORTANCE: Autochthonous B. canis infections in Berlin/Brandenburg were associated with severe clinicopathological changes, SIRS, and multiorgan involvement. Testing by PCR during and after treatment is advisable to monitor treatment success. Screening of blood donors in high-risk areas and year-round tick protection is strongly recommended.
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