Evidence map›Paper›PMID 36629623›Full record

ArticleActa cirurgica brasileira2023

Anacardium occidentale L. (cajueiro) in the healing of skin wounds: an experimental study in rats.

Dafni Cleia Gaia da Silva, Hanna Machado da Silva, Pedro Pastorini Franco, Tomaz José Aquino Vasconcelos do Carmo, Deivid Ramos Dos Santos, Edvaldo Lima Silveira, Ana Carla Godinho Pinto, Marcieni Ataíde de Andrade, Rosa Helena de Figueiredo Chaves

Abstract read
In one paragraph

Article in Acta cirurgica brasileira, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Dafni Cleia Gaia da SilvaGraduate student. Centro Universitário do Estado do Pará - School of Medicine - Belém (PA), Brazil.ORCID http://orcid.org/0000-0002-1432-6488
Hanna Machado da SilvaGraduate student. Centro Universitário do Estado do Pará - School of Medicine - Belém (PA), Brazil.ORCID http://orcid.org/0000-0002-8889-332X
Pedro Pastorini FrancoGraduate student. Centro Universitário do Estado do Pará - School of Medicine - Belém (PA), Brazil.ORCID http://orcid.org/0000-0002-1870-8467
Tomaz José Aquino Vasconcelos do CarmoGraduate student. Centro Universitário do Estado do Pará - School of Medicine - Belém (PA), Brazil.ORCID http://orcid.org/0000-0002-4637-3414
Deivid Ramos Dos SantosFellow Master degree. Universidade do Estado do Pará - Surgery and Experimental Research - Belém (PA), Brazil.ORCID http://orcid.org/0000-0002-7558-0359
Edvaldo Lima SilveiraPhD. Universidade do Estado do Pará - Tropical Medicine - Laboratory for Morphophysiology - Belém (PA), Brazil.ORCID http://orcid.org/0000-0002-9876-779X
Ana Carla Godinho PintoPhD, Associate professor. Faculty of Pharmaceutical Sciences of Universidade Federal do Pará - Experimental Research Group - Belém (PA), Brazil.ORCID http://orcid.org/0000-0001-7498-8865
Marcieni Ataíde de AndradePhD, Associate professor. Faculty of Pharmaceutical Sciences of Universidade Federal do Pará - Experimental Research Group - Belém (PA), Brazil.ORCID http://orcid.org/0000-0001-5875-695X
Rosa Helena de Figueiredo ChavesPhD, Associate professor. Centro Universitário do Estado do Pará - Experimental Research Group - Belém (PA), Brazil.ORCID http://orcid.org/0000-0003-3335-8845

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo analyze the effects of Anacardium occidentale Linn on the healing of skin wounds.

methodsTwenty Wistar male rats were distributed into four groups (with five animals each one): negative control group (NCG), treated with saline solution; cashew tree group (CG), treated with hydroalcoholic extract of the bark of A. occidentale Linn; manipulated cashew tree group (MCG), with the ointment of extract of the bark of A. occidentale Linn; positive control group (PCG), treated with sunflower oil. All animals were examined daily, observing the macroscopic aspects of the surgical wound. Hematoxylin-eosin staining was used for tissue morphology analysis and Masson's trichrome for better collagen fiber characterization.

resultsOn day 7, the MCG group had the expansion of the surgical wound covered by crust, exceeding the initial limits. On day 21, the wounds were observed to be completely closed and epithelialized in the NCG and CG groups. PCG and MCG still had remnants of crusts on the wound. The NCG was the only one not to present an abscess in histopathological analysis.

conclusionsThere was a prolongation of the healing phase of the animals treated with the extract, and the animals in the NCG showed a better outcome by histological analysis.

Indexed as

AnacardiumSurgical WoundAnimalsPlant ExtractsRatsRats, WistarSkinWound HealingPlant Extracts

Identifiers

PMID36629623
PMCPMC10624227

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.