ArticleArquivos brasileiros de cardiologia2023
Characteristics of Older Patients with Takayasu's Arteritis: A Two-Center, Cross-Sectional, Retrospective Cohort Study.
Article in Arquivos brasileiros de cardiologia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.
- Prevalence and clinical severity of takayasu arteritis angiographic types: a systematic review with meta-analysis.Rheumatology international · 2025Pooled it
- Factors Associated With the High Prevalence of Metabolic Syndrome in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis.Arquivos brasileiros de cardiologia · 2026Article
- A retrospective cohort study of 203 patients with Takayasu arteritis: experience from a Brazilian tertiary center.Advances in rheumatology (London, England) · 2025Article
- The vasodilatory effect of acupuncture and medicine-cake-separated moxibustion on a 28-year course of Takayasu arteritis: a case report.Frontiers in cardiovascular medicine · 2025Article
- Age and sex differentially shape brain networks in Parkinson's disease.CNS neuroscience & therapeutics · 2023Article
- Takayasu's Arteritis: Is Age a Differential Factor in the Diagnosis, Follow-Up, and Treatment of the Disease?Arquivos brasileiros de cardiologia · 2023Article
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7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFew studies have assessed elderly patients with Takayasu's arteritis (TAK).
objectivesTo evaluate the progression of TAK in different age groups and its possible effects on drug treatment and disease activity.
methodsThis cross-sectional and retrospective cohort study included 66 TAK patients. Patients were interviewed and data of the 12 preceding months were collected from electronic medical records. The patients were divided into four quartiles according to current age and compared for clinical and laboratory data, treatment, comorbidities, disease status, and functional status. Statistical significance was set at p<0.05.
resultsThe groups were Q1(22-36 years, n=16), Q2(37-42 years, n=18), Q3(43-49 years, n=17), and Q4(51-66 years, n=15). The frequency of patients with disease activity, fatigue, comorbidities and vascular impairments, and the TAK disease extent index were also comparable between the groups. With age, disease duration was longer (p=0.001), fewer patients used prednisone (Q1:43.8%, Q2:33.3%, Q3:11.8%, and Q4:6.7%; p=0.049) and immunosuppressive drugs [Q1:100.0%, Q2:66.7%, Q3:58.8%, and Q4:46.7%; Q1 versus Q3 (p=0.043), and Q1 versus Q4 (p=0.005) in post-hoc analyses], and patients had greater functional status impairment (Q2 versus Q3, p=0.003). In addition, the levels of disease damage, new TAK symptoms, and complications in the preceding 12 months were not different between the groups.
conclusionsOlder patients with TAK require minimal drug treatment, and have greater impairment of functional status, which may be attributed to aging-related factors.
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