ArticleArquivos brasileiros de cardiologia2023
Systemic Immune Inflammation Index is a Novel Marker in Predicting the Presence and Severity of Isolated Coronary Artery Ectasia.
Article in Arquivos brasileiros de cardiologia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 7 citations in OpenAlex.
- [Neutrophil-lymphocyte ratio and retinopathy in patients with type 2 diabetes mellitus].Revista medica del Instituto Mexicano del Seguro Social · 2026Observational
- Article
- Systemic immune-inflammation Index is an independent risk factor for Major adverse cardiovascular events in patients with coronary artery ectasia.Frontiers in cardiovascular medicine · 2026Article
- Rivaroxaban plus antiplatelet therapy for coronary artery ectasia: 36-month outcomes and risk prediction from a retrospective cohort study.Frontiers in cardiovascular medicine · 2026Article
- The dietary inflammatory index is associated with the presence and severity of coronary artery disease.Journal of health, population, and nutrition · 2025Article
- Novel predictive factor for erectile dysfunction: systemic immune inflammation index.International journal of impotence research · 2025Article
- How Effective is the Systemic Inflammatory Immune Index in the Etiopathogenesis of Isolated Coronary Artery Ectasia?Reply.Arquivos brasileiros de cardiologia · 2023Article
- Combined diagnostic value of the systemic immune-inflammation index and LDL for coronary microvascular disease: a retrospective cohort study.Therapeutic advances in cardiovascular diseaseArticle
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9 authors at 3 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundThe underlying pathology of isolated coronary artery ectasia (CE) has not been fully elucidated.
objectiveWe aimed to examine the relationship between the systemic immune inflammation index (Sıı), which corresponds to the multiplying of the neutrophil-to-lymphocyte ratio (NLR) and the platelet counts, and isolated CE.
methodThe retrospective study population included 200 patients with isolated CE, 200 consecutive with obstructive coronary artery disease, and 200 consecutive with a normal coronary artery angiogram. A 2-sided p-value of <0.05 was considered significant.
resultsSıı, NLR, platelet-to-lymphocyte ratio (PLR), and monocyte-to-high density lipoprotein cholesterol ratio (MHR) were significantly higher in the CE group compared with the other groups (all p<0.001). In multivariate analysis, Sıı (p<0.001, OR = 1.005, 95% CI =1.004-1.005) was found to be an independent predictor of isolated CE. In Receiver Operating Characteristic curve analysis, Sıı had a higher Area Under the Curve than NLR, PLR, and MHR. Sıı value of >517.35 has 79% sensitivity, 76% specificity for the prediction of the CE [AUC: 0.832, (p<0.001)]. Sıı had a significant correlation with the number of ectatic coronary arteries and Markis classification (r:0.214 p=0.002; r:-0.195, p=0.006, respectively).
conclusionTo the best of our knowledge, this is the first study that Sıı was significantly associated with isolated CE presence and anatomical severity.
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