Evidence map›Paper›PMID 36629427›Full record

ReviewJournal of enzyme inhibition and medicinal chemistry2023

Selected strategies to fight pathogenic bacteria.

Aiva Plotniece, Arkadij Sobolev, Claudiu T Supuran, Fabrizio Carta, Fredrik Björkling, Henrik Franzyk, Jari Yli-Kauhaluoma, Koen Augustyns, Paul Cos, Linda De Vooght and 4 more

Open access · goldAbstract readReview
In one paragraph

Review in Journal of enzyme inhibition and medicinal chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 50 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Sulfonamide-Based Inhibition of the β-Carbonic Anhydrase fromInternational journal of molecular sciences · 2024
    Article
  7. Review
  8. Article
  9. The good, the bad, and the ugly of metals as antimicrobials.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2024
    Review
  10. Article
  11. Antibacterial Properties of Rose Bengal Conjugated to Hyaluronic Acid.International journal of molecular sciences · 2024
    Article
  12. Article
  13. Article
  14. Inhibition of pathogenic bacterial carbonic anhydrases by monothiocarbamates.Journal of enzyme inhibition and medicinal chemistry · 2023
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 6 countries.

Aiva PlotnieceLatvian Institute of Organic Synthesis, Riga, Latvia.ORCID 0000-0003-2187-5693
Arkadij SobolevLatvian Institute of Organic Synthesis, Riga, Latvia.ORCID 0000-0002-5517-1240
Claudiu T SupuranDepartment of NEUROFARBA, Section of Pharmaceutical and Nutraceutical Sciences, University of Florence, Firenze, Italy.ORCID 0000-0003-4262-0323
Fabrizio CartaDepartment of NEUROFARBA, Section of Pharmaceutical and Nutraceutical Sciences, University of Florence, Firenze, Italy.ORCID 0000-0002-1141-6146
Fredrik BjörklingDepartment of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, Center for Peptide-Based Antibiotics, University of Copenhagen, Copenhagen East, Denmark.ORCID 0000-0001-7018-8334
Henrik FranzykDepartment of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, Center for Peptide-Based Antibiotics, University of Copenhagen, Copenhagen East, Denmark.ORCID 0000-0002-2822-1927
Jari Yli-KauhaluomaDivision of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, Drug Research Program, University of Helsinki, Helsinki, Finland.ORCID 0000-0003-0370-7653
Koen AugustynsInfla-Med, Centre of Excellence, University of Antwerp, Antwerp, Belgium.ORCID 0000-0002-5203-4339
Paul CosDepartment of Pharmaceutical Sciences, Laboratory for Microbiology, Parasitology and Hygiene (LMPH), University of Antwerp, Antwerp, Belgium.ORCID 0000-0003-4361-8911
Linda De VooghtDepartment of Pharmaceutical Sciences, Laboratory for Microbiology, Parasitology and Hygiene (LMPH), University of Antwerp, Antwerp, Belgium.ORCID 0000-0002-8425-8601
Matthias GovaertsDepartment of Pharmaceutical Sciences, Laboratory for Microbiology, Parasitology and Hygiene (LMPH), University of Antwerp, Antwerp, Belgium.ORCID 0000-0002-1290-0968
Juliana AizawaDepartment of Pharmaceutical Sciences, Laboratory for Microbiology, Parasitology and Hygiene (LMPH), University of Antwerp, Antwerp, Belgium.ORCID 0000-0003-1778-9469
Päivi TammelaDivision of Pharmaceutical Biosciences, Faculty of Pharmacy, Drug Research Program, University of Helsinki, Helsinki, Finland.ORCID 0000-0003-4697-8066
Raivis ŽalubovskisLatvian Institute of Organic Synthesis, Riga, Latvia.ORCID 0000-0002-9471-1342
University of Antwerp · BELatvijas Organiskās Sintēzes Institūts · LVUniversity of Copenhagen · DKUniversity of Florence · ITUniversity of Helsinki · FIRiga Technical University · LV

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural products and analogues are a source of antibacterial drug discovery. Considering drug resistance levels emerging for antibiotics, identification of bacterial metalloenzymes and the synthesis of selective inhibitors are interesting for antibacterial agent development. Peptide nucleic acids are attractive antisense and antigene agents representing a novel strategy to target pathogens due to their unique mechanism of action. Antisense inhibition and development of antisense peptide nucleic acids is a new approach to antibacterial agents. Due to the increased resistance of biofilms to antibiotics, alternative therapeutic options are necessary. To develop antimicrobial strategies, optimised

Indexed as

Anti-Infective AgentsPeptide Nucleic AcidsAnti-Bacterial AgentsBacteriaBiofilmsAnti-Bacterial AgentsAnti-Infective AgentsPeptide Nucleic AcidsAntimicrobialsbiofilmsbiopharmaceuticalsmetalloenzymesnatural products

Identifiers

PMID36629427
PMCPMC9848314
OpenAlexW4315619539

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.