Evidence map›Paper›PMID 36629421›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2023

Design and synthesis of novel rigid dibenzo[

Mohammed Farrag El-Behairy, Walaa Hamada Abd-Allah, Mohamed M Khalifa, Mohamed S Nafie, Mohamed A Saleh, Mohammed S Abdel-Maksoud, Tarfah Al-Warhi, Wagdy M Eldehna, Ahmed A Al-Karmalawy

Abstract read
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Review
  3. Click synthesis of some novel benzo[RSC medicinal chemistry · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mohammed Farrag El-BehairyDepartment of Organic and Medicinal Chemistry, Faculty of Pharmacy, University of Sadat City, Menoufiya, Egypt.ORCID 0000-0001-7843-1423
Walaa Hamada Abd-AllahPharmaceutical Chemistry Department, Collage of Pharmaceutical Science and Drug Manufacturing, Misr University for Science and Technology, Giza, Egypt.
Mohamed M KhalifaPharmaceutical Medicinal Chemistry and Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.ORCID 0000-0002-8146-993X
Mohamed S NafieChemistry Department, Faculty of Science, Suez Canal University, Ismailia, Egypt.ORCID 0000-0003-4454-6390
Mohamed A SalehDepartment of Clinical Sciences, College of Medicine, University of Sharjah, Sharjah, The United Arab Emirates.
Mohammed S Abdel-MaksoudMedicinal and Pharmaceutical Chemistry Department, Pharmaceutical and Drug Industries Research Institute, National Research Centre (ID: 60014618), Giza, Egypt.
Tarfah Al-WarhiDepartment of Chemistry, College of Science, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
Wagdy M EldehnaDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt.ORCID 0000-0001-6996-4017
Ahmed A Al-KarmalawyPharmaceutical Chemistry Department, Faculty of Pharmacy, Ahram Canadian University, Giza, Egypt.ORCID 0000-0002-8173-6073

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this research, two novel series of dibenzo[

Indexed as

Antineoplastic AgentsLeukemiaAzepinesCell Line, TumorCell ProliferationDNADNA Topoisomerases, Type IIDoxorubicinDrug Screening Assays, AntitumorHumansIntercalating AgentsMolecular Docking SimulationMolecular StructureStructure-Activity RelationshipTopoisomerase II InhibitorsAntineoplastic AgentsAzepinesDNADNA Topoisomerases, Type IIDoxorubicinIntercalating AgentsTopoisomerase II InhibitorsDibenzo[bf]azepinesin vivorigidificationring closureSARtopoisomerase II

Identifiers

PMID36629421
PMCPMC9848257

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.