ArticleLung India : official organ of Indian Chest Society
Diagnostic yield of CBNAAT in the diagnosis of extrapulmonary tuberculosis: A prospective observational study.
Article in Lung India : official organ of Indian Chest Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Article
- Maxillofacial tubercular osteomyelitis: diagnostic and therapeutic perspectives from a case series.BMC infectious diseases · 2026Article
- Comparison of the treatment outcomes and identification of the risk factors associated with unfavorable outcomes among extra pulmonary and pulmonary tuberculosis patients under NTEP.BMC infectious diseases · 2026Article
- Clinico-microbiological study of extrapulmonary tuberculosis from a teaching institute in North India.Journal of family medicine and primary care · 2026Article
- Role of CBNAAT and ADA in tubercular pleural effusion diagnosis at BMGMC hospital.Bioinformation · 2026Article
- Case Report: Foreign Body-induced Pseudomonas Arthritis Mimicking Tuberculous Ankle Infection in a Child.Journal of orthopaedic case reports · 2026Article
- Article
- Article
- Article
- Lessons for the clinical nephrologist: a rare presentation of extrapulmonary tuberculosis in a hemodialysis patient.Journal of nephrology · 2025Article
- Primary Thyroid Tuberculosis Diagnosed with CBNAAT.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025Article
- Cartridge-based nucleic amplification (CBNAAT)/GeneXpert test as a diagnostic modality for the detection of genital tuberculosis in women with infertility.GMS infectious diseases · 2025Article
- Syrian civil war and assessment of tuberculosis among Syrian refugees and local citizens in Mardin.Frontiers in public health · 2025Article
- Tuberculous pyomyositis presenting as septic arthritis and multiple site pyomyositis.BMJ case reports · 2024Article
- Pleomorphic adenoma of the parotid gland concomitant with tuberculosis infection: A case report and review of the literature.SAGE open medical case reports · 2024Article
- Clinical Application of theInfection and drug resistance · 2023Article
- Abdominal Tuberculosis Masquerading as Malignancy in an Infant.Journal of Indian Association of Pediatric SurgeonsArticle
- Gingiva as the primary site of extrapulmonary tuberculosis: A rare case report with brief review of literature.Journal of Indian Society of PeriodontologyArticle
- Role of percutaneous CT-guided biopsy in the characterisation of pleural diseases.Lung India : official organ of Indian Chest SocietyArticle
- Diagnostic Efficacy of New Xpert Ultra for Extrapulmonary Tuberculosis Using Culture and Composite Reference Standard.International journal of applied & basic medical researchArticle
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6 authors.
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Abstract
Background: Extrapulmonary Tuberculosis (EPTB) accounts for 15%-53% of all TB cases. In recent years, cartridge-based nucleic acid amplification test (CBNAAT) has emerged as an important diagnostic tool since the diagnostic yield is higher. We conducted this study to evaluate the diagnostic yield of CBNAAT in EPTB. Methods: One hundred and four patients with EPTB were included in the study. Samples were subjected to CBNAAT, AFB smear, culture for Mycobacterium tuberculosis and histopathology examination (HPE). Yield of each was estimated as compared to a composite reference standard (CRS). Results: The most common EPTB was lymph node TB (48.1%). CBNAAT was positive in 30.76% of EPTB cases. The highest yield was for bone and joint TB (35.7%), followed by lymph node TB (34%) and abdominal TB (33.3%). Taking CRS as the gold standard, sensitivity of CBNAAT was 32.3%, that of AFB culture was 33.3% and that of HPE was 87.2%. Conclusion: When taken as a single diagnostic tool, HPE had highest sensitivity in diagnosing EPTB when compared to CBNAAT and AFB culture. Use of CBNAAT alone for diagnosis of EPTB may result in missing the diagnosis. A combined modality incorporating CBNAAT, histopathology and AFB culture is the best approach for diagnosis of EPTB.
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