Evidence map›Paper›PMID 36629065›Full record

ArticleInvestigative and clinical urology2023

Effect of male age on reproductive function: A comparison of young and middle-aged men.

Tae Ho Lee, Dong Suk Kim, Dae Keun Kim, Dong Hyuk Shin, Mihee Oh, Won Hee Lee, Seung-Hun Song

Open access · diamondAbstract read
In one paragraph

Article in Investigative and clinical urology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Long-Term Epidemiological Trends and Regional Disparities in Male Infertility in Central Asia (1991-2023).International journal of environmental research and public health · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Tae Ho Lee *Department of Urology, CHA Fertility Center Gangnam, CHA Gangnam Medical Center, CHA University, Seoul, Korea.ORCID 0000-0002-6797-1042
Dong Suk Kim *Department of Urology, CHA Fertility Center Gangnam, CHA Gangnam Medical Center, CHA University, Seoul, Korea.ORCID 0000-0001-7350-0303
Dae Keun KimDepartment of Urology, CHA Fertility Center, Seoul Station, CHA University, Seoul, Korea.ORCID 0000-0003-3237-6304
Dong Hyuk ShinCHA Fertility Center Gangnam, CHA University, Seoul, Korea.ORCID 0000-0002-9789-237X
Mihee OhCHA Fertility Center Gangnam, CHA University, Seoul, Korea.ORCID 0000-0002-2880-5738
Won Hee LeeCHA Fertility Center Gangnam, CHA University, Seoul, Korea.ORCID 0000-0001-5816-0021
Seung-Hun SongDepartment of Urology, CHA Fertility Center Gangnam, CHA Gangnam Medical Center, CHA University, Seoul, Korea. shsong02@cha.ac.kr.ORCID 0000-0003-4649-9129
CHA University Gangnam Medical Center · KRMaria Fertility Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThere have been concerns regarding potential effects of older paternal age on male reproductive function. However, currently available data on this topic are insufficient and controversy exists. We analyzed semen characteristics and reproductive hormones in young men and middle-aged men to investigate the effect of age on male reproductive function. MATERIALS AND

methodsThis study examined healthy males of reproductive age who visited a single infertility center from January 2016 to July 2021. The young group consisted of men who were less than 35 years-old, and the middle-age group consisted of men who were more than 45 years-old.

resultsThe two groups had no significant differences in sperm concentration ([89.9±59.4]×10

conclusionsOur results suggest that advanced male age might have a negative effect on fertility potential, as in women. This finding has important clinical implications because more couples are choosing to have children when they are older. Further studies on this issue, especially those that examine reproductive outcome, are warranted.

Indexed as

SemenSperm MotilityAdultChildFemaleFollicle Stimulating HormoneHumansMaleMiddle AgedSemen AnalysisSperm CountFollicle Stimulating HormonePaternal ageReproductive healthSemen analysis

Identifiers

PMID36629065
PMCPMC9834564
OpenAlexW4312283144

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.