Evidence map›Paper›PMID 36628508›Full record

ArticlePharmacology research & perspectives2023

Comparison of creatinine-based equations for estimating renal function for digoxin dose adjustment in patients with atrial fibrillation and heart failure.

Masahiro Sakai, Toshinori Hirai, Satoshi Shitara, Takuya Iwamoto, Tsuyoshi Shiga

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmacology research & perspectives, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Masahiro SakaiThe Jikei University School of Medicine, Tokyo, Japan.
Toshinori HiraiDepartment of Clinical Pharmacology and Therapeutics, The Jikei University School of Medicine, Tokyo, Japan.ORCID 0000-0002-3898-2068
Satoshi ShitaraDepartment of Clinical Pharmacology and Therapeutics, The Jikei University School of Medicine, Tokyo, Japan.
Takuya IwamotoDepartment of Pharmacy, Mie University Hospital, Faculty of Medicine, Mie University, Tsu, Mie, Japan.ORCID 0000-0002-6445-4410
Tsuyoshi ShigaDepartment of Clinical Pharmacology and Therapeutics, The Jikei University School of Medicine, Tokyo, Japan.ORCID 0000-0003-0358-7196
Jikei University School of Medicine · JPMie University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to determine an appropriate equation for estimating renal function to dose regulate the serum digoxin trough concentration to a target of <0.9 ng/ml in patients with atrial fibrillation (AF) and heart failure (HF). All patients received 0.125 mg oral digoxin daily. The estimated glomerular filtration rate by the Modification of Diet in Renal Disease (eGFR

Indexed as

Atrial FibrillationHeart FailureRenal Insufficiency, ChronicCreatinineDigoxinGlomerular Filtration RateHumansKidneyCreatinineDigoxinatrial fibrillationdigoxinequationglomerular filtration rateheart failuretherapeutic drug monitoring

Identifiers

PMID36628508
PMCPMC9832284
OpenAlexW4315619229

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.