Evidence map›Paper›PMID 36628244›Full record

ArticleAmerican journal of translational research2022

Characterization of global research hotspots and trends on ten-eleven translocation 2: visualization and bibliometric analysis.

Hao Lv, Ziang Gao, Yunfei Wang, Peiqiang Liu, Danxue Qin, Huiqin Zhou, Yu Xu

Abstract read
In one paragraph

Article in American journal of translational research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hao LvDepartment of Otolaryngology-Head and Neck Surgery, Renmin Hospital of Wuhan University Wuhan, Hubei, China.
Ziang GaoDepartment of Otolaryngology-Head and Neck Surgery, Renmin Hospital of Wuhan University Wuhan, Hubei, China.
Yunfei WangDepartment of Otolaryngology-Head and Neck Surgery, Renmin Hospital of Wuhan University Wuhan, Hubei, China.
Peiqiang LiuDepartment of Otolaryngology-Head and Neck Surgery, Renmin Hospital of Wuhan University Wuhan, Hubei, China.
Danxue QinDepartment of Otolaryngology-Head and Neck Surgery, Renmin Hospital of Wuhan University Wuhan, Hubei, China.
Huiqin ZhouDepartment of Otolaryngology-Head and Neck Surgery, Renmin Hospital of Wuhan University Wuhan, Hubei, China.
Yu XuDepartment of Otolaryngology-Head and Neck Surgery, Renmin Hospital of Wuhan University Wuhan, Hubei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectiveTen-eleven translocation-2 (TET2) is member of the methylcytosine dioxygenase family and plays important roles in a variety of physiological and pathological processes; however, no bibliometric analysis has been performed to methodically evaluate the scientific research on TET2. Therefore, the aim of this study was to conduct a visual and scientometric analysis of TET2 research and to explore its current landscape, future direction, and research frontiers.

methodsPublications related to TET2 research were retrieved from the Web of Science Core Collection (WoSCC) from 2009 to 2021. Excel, CiteSpace, and VOSviewer were utilized to perform the bibliometric visualization analysis.

resultsA total of 2384 articles were retrieved. The number of publications on TET2 has been steadily increasing from 2009 to 2021. The USA is the top contributor to the topic, with the largest number of publications. Harvard University and the Institut National de la Santé et de la Recherche Médicale were the leading institutions, while Levine RL of Memorial Sloan-Kettering Cancer Center is the most prolific and influential author. In TET2-related publications, the high-frequency keywords were: "tet2", "DNA methylation", "5-hrdroxymethylcytosine", "5-methylcytosine", "mutations", and "acute myeloid-leukemia". Based on keyword bursts, the emerging TET2 research hotspots include "inflammation", "gene expression", "landscape", and "clonal hematopoiesis".

conclusionResearch on TET2 is constantly growing and evolving during the last decade. Here, we provide an objective and comprehensive analysis of the global status, research hotspots, and potential trends in the field of TET2 research by using a bibliometric approach. These results will assist researchers in mastering the knowledge structure and guiding the future research directions of TET2.

Indexed as

bibliometric analysisCiteSpaceDNA methylationTET2VOSviewer

Identifiers

PMID36628244
PMCPMC9827328

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.