ArticleAmerican journal of translational research2022
Radiomics analysis of unaffected side changes in classic trigeminal neuralgia.
Article in American journal of translational research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- A comprehensive evaluation of non-vascular prepontine cistern anatomy influencing trigeminal nerve vulnerability using machine learning-based morphometric analysis.Frontiers in medicine · 2026Article
- Radiomic Applications in Skull Base Pathology: A Systematic Review of Potential Clinical Uses.Journal of neurological surgery. Part B, Skull base · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the subtle differences in the structure of the unaffected trigeminal nerve between patients with classic trigeminal neuralgia (CTN) and healthy controls (HCs) by means of radiomics, so as to further explore the etiological mechanism of trigeminal neuralgia (TN).
methodsThe imagine data of 95 CTN patients and 89 matched HCs were collected and retrospectively analyzed. They were assigned to four groups according to the presence or absence of neurovascular compression (NVC) of the unaffected trigeminal nerve (HCs with and without NVC; CTN patients with and without NVC on the unaffected side). All patients underwent magnetic resonance imaging (MRI) scans. Bilateral trigeminal cisternal segments were manually delineated, followed by feature extraction, dimensionality reduction, feature selection, model construction and model evaluation.
resultsSix weighted textural signatures (sphericity, maximum 2D diameter, skewness, robust mean absolute deviation, large dependence low gray level emphasis, and surface-to-volume ratio) were found in HCs with and without NVC, while 7 were found in CTN patients without NVC on the unaffected side and HCs without NVC. The Rad_score was statistically different between the two groups (
conclusionsNVC can alter trigeminal nerve structure and cause alterations in related characteristics; but NVC is not a necessary condition for the formation of CTN, and its incidence is also high in asymptomatic healthy people, and thus it is necessary to grade the severity of NVC. In addition, there are differences in the characteristics of the unaffected side between CTN patients and HCs, which may be due to congenital or secondary factors.
Indexed as
Identifiers
36628234PMC9827329What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.