Evidence map›Paper›PMID 36628222›Full record

ArticleAmerican journal of translational research2022

A tract-based spatial statistics study of white matter integrity in epilepsy.

Xiao-Xia Hou, Hong-Xuan Feng, Bo Xu, Zhi-Sen Li, Yan-Li Lu, Hui-Min Zhao, Mei-Xia Wang, Qian-Ru Shi, Qian Gui, Guan-Hui Wu and 7 more

Abstract read
In one paragraph

Article in American journal of translational research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

17 authors.

Xiao-Xia HouDepartment of Neurology, The Affiliated Suzhou Hospital of Nanjing Medical University (Suzhou Municipal Hospital) Suzhou 215002, Jiangsu, China.
Hong-Xuan FengDepartment of Neurology, The Affiliated Suzhou Hospital of Nanjing Medical University (Suzhou Municipal Hospital) Suzhou 215002, Jiangsu, China.
Bo XuDepartment of Neurology, The Affiliated Suzhou Hospital of Nanjing Medical University (Suzhou Municipal Hospital) Suzhou 215002, Jiangsu, China.
Zhi-Sen LiDepartment of Radiology, The Affiliated Suzhou Hospital of Nanjing Medical University (Suzhou Municipal Hospital) Suzhou 215002, Jiangsu, China.
Yan-Li LuDepartment of Radiology, The Affiliated Suzhou Hospital of Nanjing Medical University (Suzhou Municipal Hospital) Suzhou 215002, Jiangsu, China.
Hui-Min ZhaoDepartment of Neurology, The Affiliated Suzhou Hospital of Nanjing Medical University (Suzhou Municipal Hospital) Suzhou 215002, Jiangsu, China.
Mei-Xia WangDepartment of Neurology, The Affiliated Suzhou Hospital of Nanjing Medical University (Suzhou Municipal Hospital) Suzhou 215002, Jiangsu, China.
Qian-Ru ShiDepartment of Neurology, The Affiliated Suzhou Hospital of Nanjing Medical University (Suzhou Municipal Hospital) Suzhou 215002, Jiangsu, China.
Qian GuiDepartment of Neurology, The Affiliated Suzhou Hospital of Nanjing Medical University (Suzhou Municipal Hospital) Suzhou 215002, Jiangsu, China.
Guan-Hui WuDepartment of Neurology, The Affiliated Suzhou Hospital of Nanjing Medical University (Suzhou Municipal Hospital) Suzhou 215002, Jiangsu, China.
Ming-Qiang ShenDepartment of Neurology, The Affiliated Suzhou Hospital of Nanjing Medical University (Suzhou Municipal Hospital) Suzhou 215002, Jiangsu, China.
Wei ZhuDepartment of Neurology, The Affiliated Suzhou Hospital of Nanjing Medical University (Suzhou Municipal Hospital) Suzhou 215002, Jiangsu, China.
Qin-Rong XuDepartment of Neurology, The Affiliated Suzhou Hospital of Nanjing Medical University (Suzhou Municipal Hospital) Suzhou 215002, Jiangsu, China.
Xiao-Feng DongDepartment of Neurology, The Affiliated Suzhou Hospital of Nanjing Medical University (Suzhou Municipal Hospital) Suzhou 215002, Jiangsu, China.
Qing-Zhang ChengDepartment of Neurology, The Affiliated Suzhou Hospital of Nanjing Medical University (Suzhou Municipal Hospital) Suzhou 215002, Jiangsu, China.
Ji-Bin ZhangDepartment of Radiology, The Affiliated Suzhou Hospital of Nanjing Medical University (Suzhou Municipal Hospital) Suzhou 215002, Jiangsu, China.
Zhi-Liang DingDepartment of Neurosurgery, The Affiliated Suzhou Hospital of Nanjing Medical University (Suzhou Municipal Hospital) Suzhou 215002, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the changes of cerebral white matter diffusion tensor in epilepsy.

methodsThis study was a retrospective study based on diffusion tensor imaging (DTI). Twenty-six epileptic patients and 42 normal controls matched for sex, age and handedness were enrolled in our research. Based on the method of tract-based spatial statistics (TBSS), we analyzed the changes of each relevant parameter index of DTI in white matter of the brain in all subjects, including fractional anisotropy (FA), mean diffusivity (MD), axial diffusivity (AD) and radial diffusivity (RD).

resultsIn comparison with the control group, epileptic patients had decreased FA and elevated MD, AD, and RD in the anterior thalamic radiation, corticospinal tract, forceps major, forceps minor, cingulum, inferior fronto-occipital fasciculus, inferior longitudinal fasciculus, superior longitudinal fasciculus and uncinate fasciculus (

conclusionWidespread white matter integrity was observed in epileptic patients, which may be the structural basis for the development of affective disorders, impaired cognition, and motor abnormalities.

Indexed as

diffusion tensor imagingEpilepsytract-based spatial statisticwhiter matter

Identifiers

PMID36628222
PMCPMC9827316

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.