Evidence map›Paper›PMID 36627668›Full record

Observational studyJournal of orthopaedic surgery and research2023

Ten-year trends in the treatment and intervention timing for patients with metastatic spinal tumors: a retrospective observational study.

Ryosuke Hirota, Atsushi Teramoto, Noriyuki Iesato, Mitsumasa Chiba, Toshihiko Yamashita

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Journal of orthopaedic surgery and research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ryosuke HirotaDepartment of Orthopaedic Surgery, Sapporo Medical University School of Medicine, S1W17, Chuo-Ku, Sapporo, Hokkaido, 060-8556, Japan. rhirota1121@gmail.com.
Atsushi TeramotoDepartment of Orthopaedic Surgery, Sapporo Medical University School of Medicine, S1W17, Chuo-Ku, Sapporo, Hokkaido, 060-8556, Japan.
Noriyuki IesatoDepartment of Orthopaedic Surgery, Sapporo Medical University School of Medicine, S1W17, Chuo-Ku, Sapporo, Hokkaido, 060-8556, Japan.
Mitsumasa ChibaDepartment of Orthopaedic Surgery, Sapporo Medical University School of Medicine, S1W17, Chuo-Ku, Sapporo, Hokkaido, 060-8556, Japan.
Toshihiko YamashitaDepartment of Orthopaedic Surgery, Sapporo Medical University School of Medicine, S1W17, Chuo-Ku, Sapporo, Hokkaido, 060-8556, Japan.
Sapporo Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCancer treatment has recently evolved due to the advances in comprehensive therapies, including chemotherapy and radiotherapy. The aspect of cancer-related bone metastasis has undergone a paradigm shift with the transformation of orthopedic interventions for spinal metastasis. We performed this retrospective observational study to investigate the changes in patient status and metastatic spine-tumor treatment over the past decade.

methodsWe included 186 patients (122 men and 64 women; mean age: 67.6 years) who were referred to our hospital between 2009 and 2018 and were diagnosed and treated for metastatic spinal tumors. We classified the patients into early (81 patients from 2009 to 2013) and late (105 patients from 2014 to 2018) groups. The following components were investigated and compared between the groups: primary tumor, time taken from subjective-symptom onset to hospital visit, primary tumor evaluation during the visit, walking capacity due to lower paralysis during the visit, local treatment details, and post-treatment functional prognosis.

resultsPredominant primary tumors with similar trends in both groups included lung cancer, multiple myeloma, and prostate cancer. The percentage of non-ambulatory patients during the consultation was significantly lower in the late group (28% vs. 16%, P = 0.04). Among non-ambulatory patients at the time of hospital visit, the mean time from the primary doctor consultation to our hospital visit was 2.8 and 2.1 days in the early and late groups, respectively. In both groups, surgical procedures were performed promptly on the non-ambulatory patients; however, postoperative lower function did not improve in approximately half of the patients.

conclusionsOur findings demonstrated that in recent years, patients tended to be referred promptly from their previous doctors under a favorable collaboration system. However, the effectiveness of lower paralysis treatment remains limited, and it is important to raise awareness regarding the importance of early consultation among the general public for earlier detection.

Indexed as

Lung NeoplasmsSpinal NeoplasmsAgedFemaleHumansMalePrognosisRetrospective StudiesSpineMetastatic spinal tumorsTime from symptomWalking ability

Identifiers

PMID36627668
PMCPMC9832741
OpenAlexW4315490454

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.