Evidence map›Paper›PMID 36627663›Full record

ArticleJournal of cardiothoracic surgery2023

Morbid obesity impacts mortality among inpatients with type a aortic dissection: an analysis of the national inpatient sample.

Xiao Xu, Renqi Yin, Kangkang Zhi, Yingyi Qin, Boxiang Tu, Shengyong Wu, Ziwei Dong, Dongxu Liu, Jia He

Open access · goldAbstract read
In one paragraph

Article in Journal of cardiothoracic surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Xiao Xu *Tongji University School of Medicine, Shanghai, 200092, China.
Renqi Yin *Department of Vascular Surgery, Changzheng Hospital, Naval Medical University, Shanghai, 200433, China.
Kangkang Zhi *Department of Vascular Surgery, Changzheng Hospital, Naval Medical University, Shanghai, 200433, China.
Yingyi QinDepartment of Military Health Statistics, Naval Medical University, Shanghai, 200433, China.
Boxiang TuDepartment of Military Health Statistics, Naval Medical University, Shanghai, 200433, China.
Shengyong WuDepartment of Military Health Statistics, Naval Medical University, Shanghai, 200433, China.
Ziwei DongTongji University School of Medicine, Shanghai, 200092, China.
Dongxu LiuTongji University School of Medicine, Shanghai, 200092, China.
Jia HeTongji University School of Medicine, Shanghai, 200092, China. hejia63@yeah.net.
Second Military Medical University · CNTongji University · CNShanghai Changzheng Hospital · CN

Funding

National Natural Science Foundation of China No. 82003558Shanghai Science and Technology Development Funds 22QA1411400
6 · The paper itself

Abstract

backgroundStanford type A aortic dissection (T(A)AD) is one of the most dangerous cardiovascular diseases and morbid obesity is associated with the prognosis of many cardiovascular diseases. The aim of this study is to investigate the impact of morbid obesity on in-hospital mortality, total hospital costs and discover the prevalence of morbid obesity among inpatients with T(A)AD.

methodsPatients with a primary diagnosis of T(A)AD were identified from the National Inpatient Sample database (NIS) from 2008 to 2017. These patients were categorized into non-obesity, obesity and morbid obesity. Multivariable regression models were utilized to assess the association between obesity/morbid obesity and in-hospital mortality, total cost and other clinical factors. The temporal trend in prevalence of obesity/morbid obesity in T(A)ADs and the trend of in-hospital mortality among different weight categories were also explored.

resultsFrom the NIS database 8489 T(A)AD inpatients were identified, of which 7230 (85.2%) patients were non-obese, 822 (9.7%) were obese and 437 (5.1%) were morbid obese. Morbid obesity was associated with increased risk of in-hospital mortality (odds ratio [OR] 1.39; 95% confidence interval [CI] 1.03-1.86), 8% higher total cost compared with the non-obese patients. From 2008 to 2017, the rate of obesity and morbid obesity in patients with T(A)AD have significantly increased from 7.36 to 11.33% (P < 0.001) and from 1.95 to 7.37% (P < 0.001). Factors associated with morbid obesity in T(A)ADs included age, female, elective admission, hospital region, dyslipidemia, smoking, rheumatoid arthritis/collagen vascular diseases, chronic pulmonary disease, diabetes and hypertension.

conclusionsMorbid obesity are connected with worse clinical outcomes and more health resource utilization in T(A)AD patients. Appropriate medical resource orientation and weight management education for T(A)AD patients may be necessary.

Indexed as

Aortic DissectionCardiovascular DiseasesObesity, MorbidFemaleHospitalizationHospital MortalityHumansInpatientsRetrospective StudiesRisk FactorsIn-hospital mortalityMorbid obesityPrevalenceType A aortic dissection

Identifiers

PMID36627663
PMCPMC9832697
OpenAlexW4315490484

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.