Evidence map›Paper›PMID 36627602›Full record

ArticleBMC public health2023

Study protocol of the sweet tooth study, randomized controlled trial with partial food provision on the effect of low, regular and high dietary sweetness exposure on sweetness preferences in Dutch adults.

Eva M Čad, Claudia S Tang, Hanne B T de Jong, Monica Mars, Katherine M Appleton, Kees de Graaf

2 registry-linked trialsOpen access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in BMC public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04497974 nacompletednot on this map

Role of Long-term Dietary Sweetness Exposure on Sweetness Preferences

TypeinterventionalSponsorWageningen UniversityRan2020 to 2024Enrolled180ConditionsFood PreferencesArmsDietary intervention
NCT06725615 nawithdrawnnot on this mapstarted 2025, after this paper: background citation

Umami Exposure on MSG-induced Satiation

TypeinterventionalSponsorWageningen UniversityRan2025 to 2025Enrolled0ConditionsSensory Testing, Umami Taste Perception, Food Intake RegulationArmsRegular Umami exposure, High Umami exposure, Low Umami exposure, one-week run-in period
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Variations in basic taste perception and body mass index.Journal of diabetes and metabolic disorders · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Eva M ČadDivision of Human Nutrition and Health, Wageningen University, Wageningen, The Netherlands. eva.cad@wur.nl.ORCID 0000-0001-5681-8627
Claudia S TangDepartment of Psychology, Faculty of Science and Technology, Bournemouth University, Bournemouth, UK.
Hanne B T de JongDivision of Human Nutrition and Health, Wageningen University, Wageningen, The Netherlands.
Monica MarsDivision of Human Nutrition and Health, Wageningen University, Wageningen, The Netherlands.
Katherine M AppletonDepartment of Psychology, Faculty of Science and Technology, Bournemouth University, Bournemouth, UK.
Kees de GraafDivision of Human Nutrition and Health, Wageningen University, Wageningen, The Netherlands.
Wageningen University & Research · NLBournemouth University · GB

Funding

Top Sector Agri & Food (TKI, The Netherlands) 1.620.000
6 · The paper itself

Abstract

backgroundSeveral health organizations recommend lowering the consumption of sweet-tasting foods. The rationale behind this recommendation is that a lower exposure to sweet foods may reduce preferences for sweet tasting foods, thus lowering sugar and energy intake, and in turn aiding in obesity prevention. However, empirical data supporting this narrative are lacking. In fact, relatively little is known about the contribution of long-term sweet taste exposure on one's sweetness preferences.

methodsThe primary objective of this randomized controlled trial is to assess the effect of low, regular and high dietary sweetness exposure on preference for sweet foods and beverages, and to compare these effects between intervention groups. One hundred and eighty adults aged 18-65 years with a BMI of 18.5-30.0 kg/m DISCUSSION: This study will generate important data on the effect of dietary sweetness exposure on sweetness preferences in terms of effect size and change, duration of change and its impact on food intake, body weight status and associated health outcomes.

trial registrationThe study protocol has been registered on ClinicalTrials.gov (ID no. NCT04497974, Registered 4 August 2020, https://clinicaltrials.gov/ct2/show/NCT04497974 ) and approved by Wageningen's Medical Ethical Committee (ABR no. NL72134).

Indexed as

DietTasteAdultBody WeightFood PreferencesGlucoseHumansRandomized Controlled Trials as TopicSweetening AgentsGlucoseSweetening AgentsExposureFood preferencesSweetnessSweet tasteTaste perception

Identifiers

PMID36627602
PMCPMC9831892
OpenAlexW4315465123

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.