Evidence map›Paper›PMID 36627519›Full record

ArticleJournal of the Association for Research in Otolaryngology : JARO2023

Cholinergic Boutons are Distributed Along the Dendrites and Somata of VIP Neurons in the Inferior Colliculus.

Julia T Kwapiszewski, Luis M Rivera-Perez, Michael T Roberts

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the Association for Research in Otolaryngology : JARO, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Julia T KwapiszewskiKresge Hearing Research Institute, Department of Otolaryngology - Head and Neck Surgery, University of Michigan, MI, Ann Arbor, 48109, USA.ORCID 0000-0003-1993-7357
Luis M Rivera-PerezKresge Hearing Research Institute, Department of Otolaryngology - Head and Neck Surgery, University of Michigan, MI, Ann Arbor, 48109, USA.ORCID 0000-0002-5898-1759
Michael T RobertsKresge Hearing Research Institute, Department of Otolaryngology - Head and Neck Surgery, University of Michigan, MI, Ann Arbor, 48109, USA. microb@umich.edu.ORCID 0000-0003-2835-8752
University of Michigan · US

Funding

University of Michigan Postbaccalaureate Research Education Program (UM PREP)R25GM086262 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ALLEN, BENJAMIN · 2009 to 2024
$6.1M
Circuit Mechanisms for Auditory Processing in the Inferior ColliculusR01DC018284 · NIDCD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ROBERTS, MICHAEL THOMAS · 2020 to 2024
$2.3M
Cholinergic Modulation of VIP Neurons in the Auditory Midbrain and its Impact on the Excitability of Thalamic NeuronsF31DC019292 · NIDCD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI RIVERA-PEREZ, LUIS MIGUEL · 2020 to 2022
$117k
NIDCD NIH HHS F31 DC019292NIDCD NIH HHS R01 DC018284NIGMS NIH HHS R25 GM086262
6 · The paper itself

Abstract

Cholinergic signaling shapes sound processing and plasticity in the inferior colliculus (IC), the midbrain hub of the central auditory system, but how cholinergic terminals contact and influence individual neuron types in the IC remains largely unknown. Using pharmacology and electrophysiology, we recently found that acetylcholine strongly excites VIP neurons, a class of glutamatergic principal neurons in the IC, by activating α

Indexed as

Inferior ColliculiAnimalsCholinergic AgentsDendritesFemaleMaleMiceNeuronsPresynaptic TerminalsCholinergic AgentsAuditoryCholinergicInferior colliculusNicotinic acetylcholine receptorsVesicular acetylcholine transporterVIP

Identifiers

PMID36627519
PMCPMC10121979
OpenAlexW4315477887

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.