ArticleJournal of neural engineering2023
A geometric approach to quantifying the neuromodulatory effects of persistent inward currents on individual motor unit discharge patterns.
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Article in Journal of neural engineering, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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29citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
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Who cites it
29 citing papers in PubMed, 49 citations in OpenAlex.
- Age-related differences in motor unit discharge rate modulation across contraction levels.GeroScience · 2026Article
- Muscle cramp susceptibility is associated with muscle-specific modulation of human motoneuron discharge patterns.Experimental physiology · 2026Article
- Probabilistic inference of homonymous and heteronymous recurrent inhibition in human muscles from large-scale motor neuron recordings.Science advances · 2026Article
- Estimation of persistent inward currents contribution to inspiratory motoneuron firing in humans.The Journal of physiology · 2026Article
- Reverse engineering of motor unit discharge in multiple sclerosis reveals heterogeneity of voluntary motor commands.medRxiv : the preprint server for health sciences · 2026Article
- Isometric handgrip contraction increases tibialis anterior intrinsic motoneuron excitability in a dose-dependent manner.Experimental physiology · 2026Article
- The modulation of human motoneuron discharge patterns with contraction force in resistance- and endurance-trained individuals.Journal of applied physiology (Bethesda, Md. : 1985) · 2026Article
- Motor unit discharge properties are modestly influenced by menstrual cycle-related fluctuations in sex hormone concentrations.bioRxiv : the preprint server for biology · 2026Article
- Motor unit discharge properties of the vastii muscles and their modulation with contraction level depend on the knee-joint angle.Journal of applied physiology (Bethesda, Md. : 1985) · 2026Article
- Bed rest and endurance retraining alter persistent inward current estimates in young and older males.Frontiers in physiology · 2026Article
- Intrinsic Motoneuron Excitability Differentiates Sarcopenic, Nonsarcopenic and Athletic Ageing Phenotypes.Journal of cachexia, sarcopenia and muscle · 2025Article
- Is soleus intrinsic motor neuron excitability contributing to motor deficits in runners with Achilles tendinopathy?European journal of applied physiology · 2025Article
- Pathophysiology of voluntary motor commands at the level of the spinal motoneuron in patients with multiple sclerosis.medRxiv : the preprint server for health sciences · 2025Article
- A novel protocol to investigate the monoaminergic relationship between descending nociceptive and motor unit neuromodulation.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2025Article
- Non-homogeneous distribution of inhibitory inputs among motor units in response to nociceptive stimulation at moderate contraction intensity.The Journal of physiology · 2025Article
- Intrinsic properties of spinal motoneurons degrade ankle torque control in humans.The Journal of physiology · 2025Article
- Multiple patterns of persistent inward currents with multiple types of repetitive firings in medullary serotonergic neurons of mice: An experimental and modeling study.PLoS computational biology · 2025Article
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Corrections and comments
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Authors and funding
8 authors at 4 institutions in 2 countries.
James A BeauchampDepartment of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Chicago, IL, United States of America.ORCID 0000-0003-2288-8672
Gregory E P PearceyDepartment of Physical Therapy and Human Movement Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States of America.ORCID 0000-0002-6751-4351
Obaid U KhurramDepartment of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, United States of America.ORCID 0000-0001-9103-4713
Matthieu ChardonNorthwestern Argonne Institute for Science and Engineering (NAISE), Northwestern University, Evanston, IL, United States of America.ORCID 0000-0001-5723-3217
Y Curtis WangDepartment of Electrical and Computer Engineering, California State University, Los Angeles, Los Angeles, CA, United States of America.ORCID 0000-0003-0211-9286
Randall K PowersDepartment of Physiology and Biophysics, University of Washington School of Medicine, Seattle, WA, United States of America.
Julius P A DewaldDepartment of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Chicago, IL, United States of America.ORCID 0000-0003-0641-8400
C J HeckmanDepartment of Physical Therapy and Human Movement Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States of America.ORCID 0000-0002-1324-7278
Northwestern University · USCalifornia State University Los Angeles · USMayo Clinic in Florida · USUniversity of Washington · US
Funding
EFFECT OF NEURAL CONSTRAINTS ON MOVEMENT IN STROKER01HD039343 · NICHD · REHABILITATION INSTITUTE OF CHICAGO · PI JULIUS P DEWALD, JUN YAO · 2000 to 2026
$6.0MSupercomputer-based Models of Motoneurons for Estimating Their Synaptic Inputs in HumansR01NS125863 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Charles Heckman · 2022 to 2026
$3.3MContralesional Corticobulbospinal Structural and Functional Changes Post Stroke: Biomarkers for the upper limb flexion synergyR01NS105759 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI DEWALD, JULIUS P · 2019 to 2023
$2.7MThe Human Motor Output MapR01NS098509 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI HECKMAN, CHARLES · 2016 to 2020
$2.1MTrigeminal Nerve Stimulation in Chronic Hemiparetic StrokeF31NS120500 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI BEAUCHAMP, JAMES ANDREW · 2020 to 2022
$83kMotor neuron adaptations to satisfy diverse behavioral demandsF32HL151251 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KHURRAM, OBAID UL HAQ · 2020 to 2020
$65kNHLBI NIH HHS F32 HL151251NICHD NIH HHS R01 HD039343NINDS NIH HHS F31 NS120500NINDS NIH HHS R01 NS098509NINDS NIH HHS R01 NS105759NINDS NIH HHS R01 NS125863
Abstract
PubMed holds no abstract for this paper.
Indexed as
Muscle, SkeletalPatient DischargeAction PotentialsElectromyographyHumansMotor Neuronsmonoaminesmotor unitspersistent inward currents
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.