Evidence map›Paper›PMID 36626560›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Characterization of a glycan-binding complex of minor pilins completes the analysis of

Meriam Shahin, Devon Sheppard, Claire Raynaud, Jamie-Lee Berry, Ishwori Gurung, Lisete M Silva, Ten Feizi, Yan Liu, Vladimir Pelicic

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Meriam ShahinMedical Research Council Centre for Molecular Bacteriology and Infection, Imperial College London, SW7 2AZ London, United Kingdom.
Devon SheppardMedical Research Council Centre for Molecular Bacteriology and Infection, Imperial College London, SW7 2AZ London, United Kingdom.
Claire RaynaudMedical Research Council Centre for Molecular Bacteriology and Infection, Imperial College London, SW7 2AZ London, United Kingdom.
Jamie-Lee BerryMedical Research Council Centre for Molecular Bacteriology and Infection, Imperial College London, SW7 2AZ London, United Kingdom.
Ishwori GurungMedical Research Council Centre for Molecular Bacteriology and Infection, Imperial College London, SW7 2AZ London, United Kingdom.
Lisete M SilvaGlycosciences Laboratory, Department of Metabolism, Digestion and Reproduction, Imperial College London, W12 0NN London, United Kingdom.
Ten FeiziGlycosciences Laboratory, Department of Metabolism, Digestion and Reproduction, Imperial College London, W12 0NN London, United Kingdom.ORCID 0000-0001-6495-0329
Yan LiuGlycosciences Laboratory, Department of Metabolism, Digestion and Reproduction, Imperial College London, W12 0NN London, United Kingdom.ORCID 0000-0002-2566-6867
Vladimir PelicicMedical Research Council Centre for Molecular Bacteriology and Infection, Imperial College London, SW7 2AZ London, United Kingdom.ORCID 0000-0002-9456-4995
Imperial College London · GBCentre National de la Recherche Scientifique · FR

Funding

Biotechnology and Biological Sciences Research Council BB/D524840/1Medical Research Council MR/P022197/1Wellcome Trust 099197/Z/12/ZWellcome Trust 108430/Z/15/ZWellcome Trust 202926/Z/16/ZWellcome Trust 218304/Z/19/Z
6 · The paper itself

Abstract

Type 4 filaments (T4F)-of which type 4 pili (T4P) are the archetype-are a superfamily of nanomachines nearly ubiquitous in prokaryotes. T4F are polymers of one major pilin, which also contain minor pilins whose roles are often poorly understood. Here, we complete the structure/function analysis of the full set of T4P pilins in the opportunistic bacterial pathogen

Indexed as

Fimbriae ProteinsStreptococcus sanguisFimbriae, BacterialHumansFimbriae Proteinsadhesionpilintype 4 pili

Identifiers

PMID36626560
PMCPMC9934059
OpenAlexW4315436393

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.