ArticleMedicine2022
Lung transplantation in a woman with paraquat poisoning that led to pulmonary fibrosis-Widely reported by the media: A case report.
Article in Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 9 citations in OpenAlex.
- Indian Society of Critical Care Medicine Position Statement on the Management of Paraquat Poisoning.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2026Article
- Lung Transplantation Following Paraquat Poisoning: Time to Think.Respirology case reports · 2025Article
- Extracorporeal membrane oxygenation as a bridge to lung transplantation following paraquat poisoning.Indian journal of thoracic and cardiovascular surgery · 2025Article
- Case Report: Multifactorial weaning failure after lung transplantation in paraquat-induced pulmonary fibrosis: a case-based clinical review.Frontiers in medicine · 2025Article
- Aberrant differentiation of epithelial progenitors is accompanied by a hypoxic microenvironment in the paraquat-injured human lung.Cell discovery · 2023Article
- Case report: Lung transplantation for treatment of paraquat intoxication: timing of transplantation.Frontiers in pharmacology · 2023Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
rationaleParaquat is an extremely toxic herbicide with a high mortality rate on poisoning. It can damage vital organs, such as the lungs, liver, heart, and kidneys. In this study, we report a case of pulmonary fibrosis after paraquat poisoning in a patient who underwent a lung transplant procedure after preoperative administration of corticosteroids and immunosuppressive agents and continuous noninvasive ventilation support therapy. PATIENT CONCERNS: An 18-year-old student was hospitalized owing to diarrhea, chest pain, and gradually evolving dyspnea. DIAGNOSES: Owing to the inability to estimate the intake concentration and dose, paraquat was only detected in the urine on the 13th day, resulting in rapid progression of the disease and severe pulmonary fibrosis.
interventionsExtensive media coverage has attracted the attention of all sectors of society. The patient received financial assistance; thus, she could receive a double-lung transplant with extracorporeal membrane oxygenation (ECMO) support on the 34th day after the poisoning. OUTCOMES: Postoperatively, the girl was actively rehabilitated, adhered to anti-rejection medication, followed up regularly, and had a good prognosis. LESSONS: Lung transplantation is currently the most effective treatment for pulmonary fibrosis, and mass media campaigns can provide economic support, influence potential organ donation, and provide such patients more chances to survive.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.