ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2023
Decrease in Gait Speed Over Time Is Associated With Increase in Number of Depression Symptoms in Older Adults With Type 2 Diabetes.
Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Purpose in life and slow walking speed: cross-sectional and longitudinal associations.GeroScience · 2024Pooled it
- Associations of gait speed, grip strength, depressive symptoms, and their combinations with fracture risk in older adults.GeroScience · 2026Article
- Sarcopenia and Functional Decline in Postmenopausal Women: The Roles of Type 2 Diabetes and Physical Activity.Medical sciences (Basel, Switzerland) · 2025Article
- Ethnicity predicts long-term depressive symptom patterns in older adults with type 2 diabetes.International psychogeriatrics · 2025Article
- Dynapenia is associated with a higher risk of depressive symptoms among older adults.Frontiers in public health · 2025Article
- Burden of type 2 diabetes in working-age adults (20-54 years): a GBD 2021 analysis projecting trends to 2035 and exploring the potential benefits of physical activity.Frontiers in public health · 2025Article
- Applying contrastive pre-training for depression and anxiety risk prediction in type 2 diabetes patients based on heterogeneous electronic health records: a primary healthcare case study.Journal of the American Medical Informatics Association : JAMIA · 2024Article
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Authors and funding
7 authors.
Funding
Abstract
backgroundWe examined the cross-sectional and longitudinal relationships of motor functions with depression in older adults with type 2 diabetes (T2D).
methodsParticipants (n = 984) were from the longitudinal Israel Diabetes and Cognitive Decline (IDCD) study. They were initially cognitively normal and underwent evaluations of motor functions (grip strength and gait speed) and of depression (using the 15-item version of the Geriatric Depression Scale [GDS]) approximately every 18 months. We applied Hierarchical Linear Mixed Models (HLMM) to investigate the associations between motor functions and depression adjusting for sociodemographic, cardiovascular factors, overall cognitive score, and subjective report of exhaustion.
resultsParticipants' baseline characteristics were 72 (±5) years of age (59.6% males), 13 (±4) years of education, Mini-Mental Status Exam (MMSE) score of 28.01 (±1.78), and a GDS score of (2 ± 2.00), consistent with normal cognitive status and lack of major affective symptomatology. Slower gait speed at baseline was associated with higher GDS scores (p = .001) and with their increase over time (p = .049). A decrease in walking speed from baseline was associated with an increase in GDS scores (p = .015). Lower grip strength at baseline was associated with higher GDS scores (p = .002), but not with trajectories in GDS scores over time. A faster decrease in grip strength from baseline was associated with a faster increase in GDS scores (p = .022).
conclusionsBoth gait speed and grip strength are cross-sectionally associated with depression. However, only gait speed and its decrease over time can potentially be used to predict incident depression symptoms, thus facilitating the introduction of depression prevention strategies.
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