Evidence map›Paper›PMID 36626096›Full record

ArticleInternational microbiology : the official journal of the Spanish Society for Microbiology2023

Genomic characterization of invasive meningococcal X isolates from Brazil, 1992-2022.

Ana Paula Cassiolato, Carlos Henrique Camargo, Maria Cristina Piccoli Cecconi, Sandra Christakis, Claudia Regina Gonçalves, Karoline Rodrigues Campos, Fabio Takenori Higa, Gabriela Andrade Pereira, Camile de Moraes, Ana Paula Silva de Lemos

Abstract read
In one paragraph

Article in International microbiology : the official journal of the Spanish Society for Microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ana Paula CassiolatoCenter of Bacteriology, Instituto Adolfo Lutz (IAL), São Paulo, State of São Paulo, Brazil.
Carlos Henrique CamargoCenter of Bacteriology, Instituto Adolfo Lutz (IAL), São Paulo, State of São Paulo, Brazil.
Maria Cristina Piccoli CecconiPublic Health Laboratory, Porto Alegre, State of Rio Grande do Sul, Brazil.
Sandra ChristakisPublic Health Laboratory, Florianópolis, State of Santa Catarina, Brazil.
Claudia Regina GonçalvesStrategic Laboratory, Instituto Adolfo Lutz (IAL), São Paulo, State of São Paulo, Brazil.
Karoline Rodrigues CamposStrategic Laboratory, Instituto Adolfo Lutz (IAL), São Paulo, State of São Paulo, Brazil.
Fabio Takenori HigaCenter of Immunology, Institute Adolfo Lutz (IAL), São Paulo, State of São Paulo, Brazil.
Gabriela Andrade PereiraSecretariat of Health Surveillance, Ministry of Health, Brasília, Federal District, Brazil.
Camile de MoraesSecretariat of Health Surveillance, Ministry of Health, Brasília, Federal District, Brazil.
Ana Paula Silva de LemosCenter of Bacteriology, Instituto Adolfo Lutz (IAL), São Paulo, State of São Paulo, Brazil. ana.lemos@ial.sp.gov.br.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionInvasive meningococcal disease (IMD) is a major health problem. Given the post-COVID-19 pandemic scenario with the loosening of the non-pharmacological measures to control the virus transmission and considering the observed global reduction of meningococcal vaccination coverage, an increase in IMD cases can be expected. METHODOLOGY: Using whole-genome sequencing, we characterized six Neisseria meningitidis serogroup X (MenX) isolates recovered from IMD cases in Brazil in the last 30 years.

resultsThe predominance (66.6%, 4/6) of ST2888 presenting fHbp 160, NHBA 129, NadA 21, and PorA 19,15 was found on isolates. Two novel STs, 15458 and 15477, were described.

conclusionThis study describes the circulation of MenX lineage ST2888 in Brazil, previously reported only in Europe. Continuous universal surveillance is crucial to implement prompt public health measures aiming to prevent and control non-vaccine preventable serogroup X IMD cases.

Indexed as

COVID-19Meningococcal InfectionsNeisseria meningitidisNeisseria meningitidis, Serogroup BAntigens, BacterialBrazilGenomicsHumansPandemicsAntigens, BacterialInvasive meningococcal diseaseMeningococcal X diseaseMenXNeisseria meningitidis serogroup X

Identifiers

PMID36626096
PMCPMC9838296

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.