Evidence map›Paper›PMID 36626042›Full record

ArticleJournal of neuro-oncology2023

Healthcare utilization and costs among intracranial meningioma patients during long-term follow-up.

Kevin A Huynh, Eva C Coopmans, Amir H Zamanipoor Najafabadi, Linda Dirven, Saskia M Peerdeman, Nienke R Biermasz, Marco J T Verstegen, Wouter R van Furth, Dutch Meningioma Consortium

Erratum issuedOpen access · hybridAbstract readMulticenter Study
In one paragraph

Article in Journal of neuro-oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Kevin A Huynh *Division of Endocrinology, Department of Medicine, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.ORCID http://orcid.org/0000-0002-7137-1074
Eva C Coopmans *Division of Endocrinology, Department of Medicine, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands. e.c.coopmans@lumc.nl.ORCID http://orcid.org/0000-0003-4780-2468
Amir H Zamanipoor NajafabadiDepartment of Neurosurgery, University Neurosurgical Center Holland, Haaglanden Medical Center, and the Hague Teaching Hospitals, Leiden University Medical Center, Leiden, The Netherlands.ORCID http://orcid.org/0000-0003-2400-2070
Linda DirvenDepartment of Neurology, Leiden University Medical Center, Leiden, The Netherlands.ORCID http://orcid.org/0000-0001-9157-9895
Saskia M PeerdemanDepartment of Neurosurgery, Amsterdam University Medical Centers, Location VUmc, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0001-5691-3210
Nienke R BiermaszDivision of Endocrinology, Department of Medicine, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.ORCID http://orcid.org/0000-0001-5817-3594
Marco J T VerstegenDepartment of Neurosurgery, University Neurosurgical Center Holland, Haaglanden Medical Center, and the Hague Teaching Hospitals, Leiden University Medical Center, Leiden, The Netherlands.ORCID http://orcid.org/0000-0001-9739-7515
Wouter R van FurthDepartment of Neurosurgery, University Neurosurgical Center Holland, Haaglanden Medical Center, and the Hague Teaching Hospitals, Leiden University Medical Center, Leiden, The Netherlands.ORCID http://orcid.org/0000-0001-5208-921X
Dutch Meningioma Consortium
Leiden University Medical Center · NLAmsterdam University Medical Centers · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeFew studies have reported on healthcare utilization and costs for intracranial meningioma patients, while the tumor and its treatment profoundly affect patients' functioning and well-being. Here we evaluated healthcare utilization and costs, including their determinants.

methodsA multicenter cross-sectional study of adult meningioma patients ≥ 5 years after intervention. Patients completed three validated patient-reported outcome measures (PROMs) assessing patients 'functioning and wellbeing (SF-36, EORTC QLQ-BN20, and HADS) and a study-specific questionnaire assessing healthcare utilization over the previous twelve months. Healthcare costs of the twelve months prior were calculated using reported healthcare utilization ≥ 5 years after intervention by the Dutch Manual for Economic Evaluation in Healthcare. Determinants for healthcare utilization and costs were determined with regression analyses.

resultsWe included 190 patients with WHO grade I or II meningioma after a mean follow-up since intervention of 9.2 years (SD 4.0). The general practitioner (80.5%), physiotherapist (37.9%), and neurologist (25.4%) were visited most often by patients. Median annual healthcare costs were €871 (IQR €262-€1933). Main contributors to these costs were medication (45.8% of total costs, of which anti-seizure medication was utilized most [21.6%]), specialist care (17.7%), and physiotherapy (15.5%). Lower HRQoL was a significant determinant for higher healthcare utilization and costs.

conclusionIn patients with meningioma, medication costs constituted the largest expenditure of total healthcare costs, in particular anti-seizure medication. Particularly a lower HRQoL was a determinant for healthcare utilization and costs. A patient-specific approach aimed at improving patients' HRQoL and needs could be beneficial in reducing disease burden and functional recovery.

Indexed as

Meningeal NeoplasmsMeningiomaAdultCross-Sectional StudiesDelivery of Health CareFollow-Up StudiesHealth Care CostsHumansPatient Acceptance of Health CareQuality of LifeCostsHealthcare utilizationHealth-related quality of lifeMeningiomaPatient-reported outcomeValue-based healthcare

Identifiers

PMID36626042
PMCPMC9988802
OpenAlexW4313898428

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.