Trial reportPopulation health management2025
Racial and Ethnic Disparity in Preference-Weighted Quality of Life: Findings from the Selenium and Vitamin E Cancer Prevention Trial.
Matthew C Rock, Riha Vaidya, Cathee Till, Joseph M Unger, Dawn Hershman, Scott Ramsey, Ariel Nehemiah, Daniel Maeng, Robert Krouse
Open access · greenAbstract readRandomized Controlled Trial
In one paragraphTrial report in Population health management, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0citing papers in PubMed
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 0 citations in OpenAlex.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
9 authors at 5 institutions in 2 countries.
Matthew C RockDepartment of Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-0197-8700 Riha VaidyaSWOG Statistics and Data Management Center, Fred Hutchinson Cancer Center, Seattle, Washington, USA.
Cathee TillSWOG Statistics and Data Management Center, Fred Hutchinson Cancer Center, Seattle, Washington, USA.
Joseph M UngerSWOG Statistics and Data Management Center, Fred Hutchinson Cancer Center, Seattle, Washington, USA.
Dawn HershmanDepartment of Medicine, Columbia University Vagelos College of Physicians and Surgeons, New York, New York, USA.
Scott RamseyHutchinson Institute for Cancer Outcomes Research (HICOR), Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Ariel NehemiahDepartment of Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Daniel MaengDepartment of Psychiatry, University of Rochester Medical Center, Rochester, New York, USA.ORCID 0000-0002-1867-6629 Robert KrouseDepartment of Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Fred Hutch Cancer Center · USUniversity of Pennsylvania · USCape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa · ZAColumbia University · USUniversity of Rochester Medical Center · US
Funding
SWOG NCORP Research BaseUG1CA189974 · NCI · THE HOPE FOUNDATION · PI CHARLES D. BLANKE, DAWN HERSHMAN · 2014 to 2026
$80.6MPCPT and SELECT Cohorts: Core Infrastructure Support for Cancer ResearchU01CA182883 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI TANGEN, CATHERINE M., THOMPSON, IAN M. · 2019 to 2023
$5.4MPCPT and SELECT cohorts: Core Infrastructure Support for Cancer Research UM1CA182883 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI TANGEN, CATHERINE M., THOMPSON, IAN M. · 2013 to 2017
$5.2MSURGICAL ONCOLOGY RESEARCH TRAINING PROGRAM AT PENNT32CA251063 · NCI · UNIVERSITY OF PENNSYLVANIA · PI Ronald P. Dematteo · 2020 to 2026
$2.6MNCI NIH HHS T32 CA251063NCI NIH HHS U01 CA182883NCI NIH HHS UG1 CA189974NCI NIH HHS UM1 CA182883
6 · The paper itselfAbstract
Differences in preference-weighted health-related quality of life (HRQOL) scores by race/ethnicity may be due to social factors. Here, Short-Form Six-Dimension (SF-6D) scores are analyzed among men in a prostate cancer prevention trial to explore such differences. Selenium and vitamin E cancer prevention trial participants who completed the SF-6D at baseline, and in at least 1 of follow-up years 1, 3, and 5 were included. This study compared mean SF-6D scores across race/ethnicity at each point using a linear mixed model controlling for demographic and clinical characteristics. At baseline, 9691 men were eligible for analysis, of whom 7556 (78%) were non-Hispanic White, 1592 (16.4%) were non-Hispanic Black, and 543 (5.6%) were Hispanic. Hispanic and White participants had higher unadjusted mean SF-6D scores than Black participants at every time point (
Indexed as
EthnicityHealth Status DisparitiesProstatic NeoplasmsQuality of LifeSeleniumVitamin EAgedBlack or African AmericanHispanic or LatinoHumansMaleMiddle AgedWhiteSeleniumVitamin Ehealth disparitiespreference-weighted quality of lifeprostate cancer
Identifiers
PMID36625863
PMCPMC13014128
OpenAlexW4315435676
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