Evidence map›Paper›PMID 36625634›Full record

ArticleMicrobiology spectrum2023

Cross-Canada Variability in Blood Donor SARS-CoV-2 Seroprevalence by Social Determinants of Health.

Sheila F O'Brien, Niamh Caffrey, Qi-Long Yi, Shelly Bolotin, Naveed Z Janjua, Mawuena Binka, Caroline Quach Thanh, Derek R Stein, Amanda Lang, Amy Colquhoun and 3 more

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. SARS-CoV-2 seroprevalence in Nova Scotia blood donors.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2024
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 10 institutions in 1 country.

Sheila F O'BrienEpidemiology and Surveillance, Canadian Blood Services, Ottawa, Ontario, Canada.ORCID 0000-0002-5332-2789
Niamh CaffreyEpidemiology and Surveillance, Canadian Blood Services, Ottawa, Ontario, Canada.
Qi-Long YiEpidemiology and Surveillance, Canadian Blood Services, Ottawa, Ontario, Canada.
Shelly BolotinCenter for Vaccine Preventable Disease, University of Toronto, Toronto, Ontario, Canada.
Naveed Z JanjuaBC Centre for Disease Control, British Columbia, Vancouver, Canada.
Mawuena BinkaBC Centre for Disease Control, British Columbia, Vancouver, Canada.
Caroline Quach ThanhDepartment of Microbiology, Infectious Diseases & Immunology, Faculty of Medicine, University of Montreal, Montreal, Quebec, Canada.ORCID 0000-0002-1170-9475
Derek R SteinCadham Provincial Laboratory, Winnipeg, Manitoba, Canada.
Amanda LangRoy Romanow Provincial laboratory, Saskatchewan Health Authority, Regina, Saskatchewan, Canada.
Amy ColquhounPopulation Health Assessment, Alberta Health, Edmonton, Alberta, Canada.
Chantale PambrunMedical Affairs & Innovation, Canadian Blood Services, Ottawa, Ontario, Canada.
Cassandra N ReedmanEpidemiology and Surveillance, Canadian Blood Services, Ottawa, Ontario, Canada.
Steven J DrewsMedical Microbiology Department, Canadian Blood Services, Edmonton, Alberta, Canada.ORCID 0000-0003-2519-1109
University of Ottawa · CAUniversity of Alberta · CABC Centre for Disease Control · CACanadian Blood Services · CACentre Hospitalier Universitaire Sainte-Justine · CAPublic Health Agency of Canada · CASaskatchewan Health Authority · CAUniversity of British Columbia · CAUniversity of Manitoba · CAUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We compared the seroprevalence of SARS-CoV-2 anti-nucleocapsid antibodies in blood donors across Canadian regions in 2021. The seroprevalence was the highest in Alberta and the Prairies, and it was so low in Atlantic Canada that few correlates were observed. Being male and of young age were predictive of seropositivity. Racialization was associated with higher seroprevalence in British Columbia and Ontario but not in Alberta and the Prairies. Living in a materially deprived neighborhood predicted higher seroprevalence, but it was more linear across quintiles in Alberta and the Prairies, whereas in British Columbia and Ontario, the most affluent 60% were similarly low and the most deprived 40% similarly elevated. Living in a more socially deprived neighborhood (more single individuals and one parent families) was associated with lower seroprevalence in British Columbia and Ontario but not in Alberta and the Prairies. These data show striking variability in SARS-CoV-2 seroprevalence across regions by social determinants of health.

Indexed as

COVID-19SARS-CoV-2AdultAlbertaAntibodies, ViralBlood DonorsFemaleHumansMaleSeroepidemiologic StudiesSocial Determinants of HealthAntibodies, Viralblood donorsCanadaracializationSARS-CoV-2seroprevalencesocial determinants of health

Identifiers

PMID36625634
PMCPMC9927354
OpenAlexW4315435963

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.