Evidence map›Paper›PMID 36625571›Full record

ArticleMicrobiology spectrum2023

Riboflavin Targets the Cellular Metabolic and Ribosomal Pathways of Candida albicans

Junwen Lei, Jian Huang, Caiyan Xin, Fangyan Liu, Jinping Zhang, Yuxin Xie, Yingyu Mao, Wenbi Chen, Zhangyong Song

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
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  4. Observational
  5. Article
  6. The Antifungal Effects of Equol AgainstJournal of fungi (Basel, Switzerland) · 2025
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  11. Antifungal Effect of Vitamin DJournal of fungi (Basel, Switzerland) · 2023
    Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Junwen LeiThe Platform of Molecular Biotechnology, Public Center of Experimental Technology, School of Basic Medical Sciences, Southwest Medical University, Luzhou, People's Republic of China.
Jian HuangThe Platform of Molecular Biotechnology, Public Center of Experimental Technology, School of Basic Medical Sciences, Southwest Medical University, Luzhou, People's Republic of China.
Caiyan XinThe Platform of Molecular Biotechnology, Public Center of Experimental Technology, School of Basic Medical Sciences, Southwest Medical University, Luzhou, People's Republic of China.
Fangyan LiuThe Platform of Molecular Biotechnology, Public Center of Experimental Technology, School of Basic Medical Sciences, Southwest Medical University, Luzhou, People's Republic of China.
Jinping ZhangThe Platform of Molecular Biotechnology, Public Center of Experimental Technology, School of Basic Medical Sciences, Southwest Medical University, Luzhou, People's Republic of China.
Yuxin XieThe Platform of Molecular Biotechnology, Public Center of Experimental Technology, School of Basic Medical Sciences, Southwest Medical University, Luzhou, People's Republic of China.
Yingyu MaoThe Platform of Molecular Biotechnology, Public Center of Experimental Technology, School of Basic Medical Sciences, Southwest Medical University, Luzhou, People's Republic of China.
Wenbi ChenThe Platform of Molecular Biotechnology, Public Center of Experimental Technology, School of Basic Medical Sciences, Southwest Medical University, Luzhou, People's Republic of China.
Zhangyong SongThe Platform of Molecular Biotechnology, Public Center of Experimental Technology, School of Basic Medical Sciences, Southwest Medical University, Luzhou, People's Republic of China.ORCID 0000-0003-1190-485X
Southwest Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oropharyngeal candidiasis (OPC), which has a high incidence in immunocompromised and denture stomatitis patients, is commonly caused by Candida albicans infection and in some cases develops into disseminated candidiasis throughout the throat and esophagus, resulting in high mortality. New drugs are needed to combat OPC because of the limited treatment options currently available and increasing resistance to existing drugs. Here, we confirmed that riboflavin (RF), a cofactor of flavin adenine mononucleotide and flavin adenine dinucleotide, has broad-spectrum anti-

Indexed as

CandidiasisCandidiasis, OralAnimalsAntifungal AgentsCandidaCandida albicansMiceMicrobial Sensitivity TestsReactive Oxygen SpeciesRiboflavinRibosomesAntifungal AgentsReactive Oxygen SpeciesRiboflavinantifungal agentCandida speciesfungal metabolismoropharyngeal candidiasisriboflavin

Identifiers

PMID36625571
PMCPMC9927497
OpenAlexW4313950045

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.