Evidence map›Paper›PMID 36625531›Full record

ArticleNutrition and cancer2023

Effect of Diets Varying in Iron and Saturated Fat on the Gut Microbiota and Intestinal Inflammation: A Crossover Feeding Study among Older Females with Obesity.

Patricia G Wolf, Beatriz Penalver Bernabe, Manoela Lima Oliveira, Alyshia Hamm, Andrew McLeod, Sarah Olender, Karla Castellanos, Brett R Loman, H Rex Gaskins, Marian Fitzgibbon and 1 more

Open access · greenAbstract read
In one paragraph

Article in Nutrition and cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Patricia G WolfInstitute for Health Research and Policy, University of Illinois Chicago, Chicago, Illinois, USA.
Beatriz Penalver BernabeDepartment of Biomedical Engineering, University of Illinois Chicago, Chicago, Illinois, USA.
Manoela Lima OliveiraDepartment of Kinesiology and Nutrition, University of Illinois Chicago, Chicago, Illinois, USA.ORCID 0000-0002-6751-0684
Alyshia HammDepartment of Kinesiology and Nutrition, University of Illinois Chicago, Chicago, Illinois, USA.
Andrew McLeodInstitute for Health Research and Policy, University of Illinois Chicago, Chicago, Illinois, USA.
Sarah OlenderDepartment of Kinesiology and Nutrition, University of Illinois Chicago, Chicago, Illinois, USA.
Karla CastellanosDepartment of Medicine, University of Illinois Chicago, Chicago, Illinois, USA.
Brett R LomanDepartment of Animal Sciences, University of Illinois Urbana-Champaign, Urbana, Illinois, USA.ORCID 0000-0001-8830-7506
H Rex GaskinsDepartment of Animal Sciences, University of Illinois Urbana-Champaign, Urbana, Illinois, USA.
Marian FitzgibbonInstitute for Health Research and Policy, University of Illinois Chicago, Chicago, Illinois, USA.
Lisa Tussing-HumphreysUniversity of Illinois Cancer Center, University of Illinois Chicago, Chicago, Illinois, USA.
University of Illinois Chicago · USUniversity of Illinois Urbana-Champaign · US

Funding

The Chicago Cancer Health Equity Collaborative (ChicagoCHEC)U54CA202995 · NCI · NORTHEASTERN ILLINOIS UNIVERSITY · PI CIECIERSKI, CHRISTINA, FEINGLASS, JOSEPH M · 2015 to 2024
$9.5M
UIC CANCER PREVENTION &CONTROL RESEARCH TRAINING GRANTR25CA057699 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI FITZGIBBON, MARIAN L. · 1992 to 2017
$8.2M
Cancer Health Equity Career Development ProgramT32CA057699 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Marian L. Fitzgibbon · 2018 to 2026
$3.0M
UIC Building Interdisciplinary Research Careers in Women's Health ProgramK12HD101373 · NICHD · UNIVERSITY OF ILLINOIS AT CHICAGO · PI BUHIMSCHI, IRINA A, MAKI, PAULINE M · 2020 to 2023
$2.9M
NCI NIH HHS R25 CA057699NCI NIH HHS T32 CA057699NCI NIH HHS U54 CA202995NICHD NIH HHS K12 HD101373
6 · The paper itself

Abstract

Obesity is considered an independent risk factor for colorectal cancer (CRC). Altered nutrient metabolism, particularly changes to digestion and intestinal absorption, may play an important role in the development of CRC. Iron can promote the formation of tissue-damaging and immune-modulating reactive oxygen species. We conducted a crossover, controlled feeding study to examine the effect of three, 3-week diets varying in iron and saturated fat content on the colonic milieu and systemic markers among older females with obesity. Anthropometrics, fasting venous blood and stool were collected before and after each diet. There was a minimum 3-week washout period between diets. Eighteen participants consumed the three diets (72% Black; mean age 60.4 years; mean body mass index 35.7 kg/m

Indexed as

DietGastrointestinal MicrobiomeIntestinesDiet, High-FatFatty AcidsFemaleHumansInflammationIronMiddle AgedObesityRNA, Ribosomal, 16SFatty AcidsIronRNA, Ribosomal, 16S

Identifiers

PMID36625531
PMCPMC10023443
OpenAlexW4315436586

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.