Evidence map›Paper›PMID 36625520›Full record

ReviewAccounts of chemical research2023

Membranized Coacervate Microdroplets: from Versatile Protocell Models to Cytomimetic Materials.

Ning Gao, Stephen Mann

Open access · hybridAbstract readReview
In one paragraph

Review in Accounts of chemical research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed
20.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 133 citations in OpenAlex.

  1. Review
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  9. MgChem & bio engineering · 2026
    Article
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  15. Review
  16. Article
  17. Sequence-Modulated Active Tripeptide Condensates for Tandem Catalysis.Angewandte Chemie (International ed. in English) · 2026
    Article
  18. Dynamic Covalent Boronate Chemistry forJournal of the American Chemical Society · 2026
    Article
  19. Article
  20. Article

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Ning GaoMax Planck-Bristol Centre for Minimal Biology, School of Chemistry, University of Bristol, Cantock's Close, BristolBS8 1TS, United Kingdom.ORCID 0000-0002-7855-8739
Stephen MannMax Planck-Bristol Centre for Minimal Biology, School of Chemistry, University of Bristol, Cantock's Close, BristolBS8 1TS, United Kingdom.ORCID 0000-0003-3012-8964
Shanghai Jiao Tong University · CNUniversity of Bristol · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although complex coacervate microdroplets derived from associative phase separation of counter-charged electrolytes have emerged as a broad platform for the bottom-up construction of membraneless, molecularly crowded protocells, the absence of an enclosing membrane limits the construction of more sophisticated artificial cells and their use as functional cytomimetic materials. To address this problem, we and others have recently developed chemical-based strategies for the membranization of preformed coacervate microdroplets. In this Account, we review our recent work on diverse coacervate systems using a range of membrane building blocks and assembly processes. First, we briefly introduce the unusual nature of the coacervate/water interface, emphasizing the ultralow interfacial tension and broad interfacial width as physiochemical properties that require special attention in the judicious design of membranized coacervate microdroplets. Second, we classify membrane assembly into two different approaches: (i)

Indexed as

Artificial CellsCell MembraneFatty AcidsPolymersProteinsFatty AcidsPolymersProteins

Identifiers

PMID36625520
PMCPMC9910039
OpenAlexW4313910065

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.