Evidence map›Paper›PMID 36625100›Full record

ArticleArthritis care & research2023

Birth Outcomes and Rehospitalizations Among Pregnant Women With Rheumatoid Arthritis and Systemic Lupus Erythematosus and Their Offspring.

Namrata Singh, Julianna Sabo, Deborah A Crane, David R Doody, Melissa A Schiff, Beth A Mueller

Open access · bronzeAbstract read
In one paragraph

Article in Arthritis care & research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Namrata SinghUniversity of Washington, Seattle.ORCID 0000-0001-7149-363X
Julianna SaboUniversity of Washington, Seattle.
Deborah A CraneUniversity of Washington, Seattle.
David R DoodyFred Hutchinson Cancer Research Center, Seattle, Washington.
Melissa A SchiffUniversity of New Mexico, Albuquerque, and University of Washington School of Public Health, Seattle.
Beth A MuellerFred Hutchinson Cancer Research Center and University of Washington School of Public Health, Seattle.
University of Washington · USFred Hutch Cancer Center · USUniversity of New Mexico · US

Funding

Improving shared decision-making around the use of disease modifying anti-rheumatic drugs in patients with rheumatoid arthritis and cancerK23AR079588 · NIAMS · UNIVERSITY OF WASHINGTON · PI Namrata Singh · 2022 to 2026
$821k
Pregnancy Outcomes in Women with Disabilities: Exploratory ResearchR21HD073024 · NICHD · FRED HUTCHINSON CANCER RESEARCH CENTER · PI MUELLER, BETH A · 2013 to 2014
$480k
NIAMS NIH HHS K23 AR079588NICHD NIH HHS R21 HD073024
6 · The paper itself

Abstract

objectiveTo compare obstetric/birth outcomes and rehospitalization among women with and without rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE) and their infants.

methodsThis population-based retrospective cohort study identified women with RA (n = 1,223) and SLE (n = 1,354) and unexposed women with singleton births 1987-2014 in Washington State in linked vital hospital discharge records. Outcomes, including cause-specific hospitalizations <2 years postpartum, were compared by estimating adjusted relative risks (RRs) and cause-specific rehospitalization hazard ratios (HRs) with 95% confidence intervals (95% CIs).

resultsWe observed increased risks of several adverse outcomes; RRs were often greatest for SLE. Women with RA/SLE more often required rehospitalization, most notably at <6 months postpartum (RA: 4% versus 2%; RR 2.22 [95% CI 1.62-3.04]; SLE: 6% versus 2%; RR 2.78 [95% CI 2.15-3.59]). Maternal postpartum rehospitalization was greatest for musculoskeletal conditions (RA: HR 19.1 [95% CI 13.6-26.8]; SLE: HR 29.8 [95% CI 22.1-40.1]). Infants of women with SLE more often had malformations (9% versus 6%; RR 1.46 [95% CI 1.21-1.75]), and increased mortality at <2 years (RR 2.11 [95% CI 1.21-3.67]). Infants of women with SLE also experienced more frequent rehospitalizations in their first year of life.

conclusionWomen with RA or SLE and their infants experienced adverse outcomes, particularly infants of women with SLE. Maternal/infant rehospitalization was more common; most marked in the early months postpartum. Close follow-up during these time periods is crucial to minimize adverse outcomes.

Indexed as

Arthritis, RheumatoidLupus Erythematosus, SystemicFemaleHumansPatient ReadmissionPregnancyPregnant PeopleRetrospective Studies

Identifiers

PMID36625100
PMCPMC12204603
OpenAlexW4315435786

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.