Evidence map›Paper›PMID 36624922›Full record

ArticleBrain and behavior2023

Effects of inhaling essential oils of Citrus limonum L., Santalum album, and Cinnamomum camphora on human brain activity.

Kazutaka Ueda, Tatsushi Horita, Takeshi Suzuki

Open access · goldAbstract read
In one paragraph

Article in Brain and behavior, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Relaxation effects of Shikuwasa (Contemporary clinical trials communications · 2026
    Article
  4. Investigating the Potential of Essential Oils fromPlants (Basel, Switzerland) · 2024
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Kazutaka UedaDepartment of Mechanical Engineering, Graduate School of Engineering, The University of Tokyo, Tokyo, Japan.ORCID 0000-0002-7525-5636
Tatsushi HoritaLaboratory, Nippon Kodo Co., Ltd., Tokyo, Japan.
Takeshi SuzukiLaboratory, Nippon Kodo Co., Ltd., Tokyo, Japan.
Nippon Chemical Industrial (Japan) · JPJapan Graduate School of Education University · JP

Funding

Nippon Kodo Co., Ltd.
6 · The paper itself

Abstract

introductionEssential oil inhalation has various effects on the human body. However, its effects on cognitive function and the neural basis remain unclear. We aimed to investigate the effects of inhaling lemon, sandalwood, and kusunoki essential oils on human brain activity and memory function using multichannel electroencephalography and brain source activity estimation.

methodsParticipants performed a letter 2-back working memory task during electroencephalography measurements before and after essential oil inhalation. Brain activation, task difficulty, concentration degree, and task performance were compared among the essential oils and a fragrance-free control.

resultsTask performance significantly improved after lemon essential oil inhalation. Lemon essential oil inhalation resulted in delta and theta band activation in the prefrontal cortex, including the anterior cingulate gyrus and orbitofrontal cortex, superior temporal gyrus, parahippocampal gyrus, and insula. During inhalation, persistent alpha band activation was observed in the prefrontal cortex, including the anterior cingulate gyrus. Sandalwood essential oil inhalation led to beta and gamma band activation in the prefrontal cortex, including the anterior cingulate gyrus.

conclusionOur findings demonstrate that different essential oils have specific effects on brain activity related to emotion and memory processing.

Indexed as

Cinnamomum camphoraCitrusOils, VolatileSantalumBrainHumansPlant OilsSesquiterpenesOils, VolatilePlant Oilssandalwood oilSesquiterpenesCinnamomum camphoraCitrus limonum Lessential oilhuman brainSantalum album

Identifiers

PMID36624922
PMCPMC9927848
OpenAlexW4315436015

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.