Evidence map›Paper›PMID 36624845›Full record

ArticleiScience2023

Distinct niche structures and intrinsic programs of fallopian tube and ovarian surface epithelial cells.

Guyu Qin, Eun-Sil Park, Xueqing Chen, Sen Han, Dongxi Xiang, Fang Ren, Gang Liu, Huidong Chen, Guo-Cheng Yuan, Zhe Li

Abstract read
In one paragraph

Article in iScience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Single-cell transcriptomic profiling of the neonatal oviduct and uterus reveals new insights into upper Müllerian duct regionalization.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024
    Article
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Guyu QinDivision of Genetics, Brigham and Women's Hospital, Boston, MA 02115, USA.
Eun-Sil ParkDivision of Genetics, Brigham and Women's Hospital, Boston, MA 02115, USA.
Xueqing ChenDivision of Genetics, Brigham and Women's Hospital, Boston, MA 02115, USA.
Sen HanDivision of Genetics, Brigham and Women's Hospital, Boston, MA 02115, USA.
Dongxi XiangDivision of Genetics, Brigham and Women's Hospital, Boston, MA 02115, USA.
Fang RenDivision of Genetics, Brigham and Women's Hospital, Boston, MA 02115, USA.
Gang LiuDivision of Genetics, Brigham and Women's Hospital, Boston, MA 02115, USA.
Huidong ChenDepartment of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Harvard School of Public Health, Boston, MA 02215, USA.
Guo-Cheng YuanDepartment of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Harvard School of Public Health, Boston, MA 02215, USA.
Zhe LiDivision of Genetics, Brigham and Women's Hospital, Boston, MA 02115, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epithelial ovarian cancer (EOC) can originate from either fallopian tube epithelial (FTE) or ovarian surface epithelial (OSE) cells, but with different latencies and disease outcomes. To address the basis of these differences, we performed single cell RNA-sequencing of mouse cells isolated from the distal half of fallopian tube (FT) and surface layer of ovary. We find at the molecular level, FTE secretory stem/progenitor cells and OSE cells resemble mammary luminal progenitors and basal cells, respectively. An FT stromal subpopulation, enriched with

Indexed as

Biological sciencesCell biologyMolecular biologyTranscriptomics

Identifiers

PMID36624845
PMCPMC9823228

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.