Evidence map›Paper›PMID 36624782›Full record

ArticleJournal of King Saud University. Science2023

The nanomolar affinity of C-phycocyanin from virtual screening of microalgal bioactive as potential ACE2 inhibitor for COVID-19 therapy.

Fiddy S Prasetiya, Wanda Destiarani, Rina F Nuwarda, Fauzian G Rohmatulloh, Wiwin Natalia, Mia T Novianti, Taufik Ramdani, Mochamad U K Agung, Sulastri Arsad, Luthfiana A Sari and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of King Saud University. Science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 2 countries.

Fiddy S PrasetiyaResearch Center for Biosystematics and Evolution, Research Organization for Life Sciences and Environment, National Research and Innovation Agency Republic of Indonesia (BRIN), Jalan Raya Bogor Km 46, Cibinong, West Java 16911, Indonesia.
Wanda DestiaraniResearch Center for Biotechnology and Bioinformatics Universitas Padjadjaran, Jl. Singaperbangsa No. 2, 40132 Bandung, Indonesia.
Rina F NuwardaDepartment of Pharmaceutical Analysis and Medicinal Chemistry, Faculty of Pharmacy, Universitas Padjadjaran, Jl. Raya Bandung Sumedang KM. 21, 45363 Jatinangor, Indonesia.
Fauzian G RohmatullohResearch Center for Biotechnology and Bioinformatics Universitas Padjadjaran, Jl. Singaperbangsa No. 2, 40132 Bandung, Indonesia.
Wiwin NataliaResearch Center for Biotechnology and Bioinformatics Universitas Padjadjaran, Jl. Singaperbangsa No. 2, 40132 Bandung, Indonesia.
Mia T NoviantiResearch Center for Biotechnology and Bioinformatics Universitas Padjadjaran, Jl. Singaperbangsa No. 2, 40132 Bandung, Indonesia.
Taufik RamdaniResearch Center for Biotechnology and Bioinformatics Universitas Padjadjaran, Jl. Singaperbangsa No. 2, 40132 Bandung, Indonesia.
Mochamad U K AgungMarine Science Department, Faculty of Fisheries and Marine Sciences, Universitas Padjadjaran, Jl. Raya Bandung Sumedang KM. 21, 45363 Jatinangor, Indonesia.
Sulastri ArsadAquatic Resources Management Study Program, Faculty of Fisheries and Marine Science, Universitas Brawijaya, Jl. Veteran, 65145 Malang, Indonesia.
Luthfiana A SariDepartment of Fish Health Management and Aquaculture, Faculty of Fisheries and Marine, Universitas Airlangga, Campus C Unair Jl. Mulyosari, 60113 Surabaya, Indonesia.
Pipit PitrianiDepartment of Coaching Education, Faculty of Sports and Health Education, Universitas Pendidikan Indonesia, Jl. Dr. Setiabudi No. 299, 40154 Bandung, Indonesia.
Suryanti SuryantiDepartment of Aquatic Resources, Faculty of Fisheries and Marine Sciences, Universitas Diponegoro, Jl. Prof. H. Soedarto, S.H., 50275 Semarang, Indonesia.
Gilang GumilarWelding and Fabrication Engineering Technology Department, Institut Teknologi Sains Bandung, Central Cikarang, 17530 Bekasi, Indonesia.
Jean-Luc MougetBiOSSE Laboratory, Faculty of Science & Technology, Le Mans Université, Avenue O. Messiaen, 72085 Le Mans Cedex 9, France.
Muhammad YusufResearch Center for Biotechnology and Bioinformatics Universitas Padjadjaran, Jl. Singaperbangsa No. 2, 40132 Bandung, Indonesia.
Padjadjaran University · IDAirlangga University · IDBandung Institute of Technology · IDDiponegoro University · IDIndonesia University of Education · IDLe Mans Université · FRNational Research and Innovation AgencyUniversity of Brawijaya · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The global pandemic of COVID-19 caused by SARS-CoV-2 has caused more than 400 million infections with more than 5.7 million deaths worldwide, and the number of validated therapies from natural products for treating coronavirus infections needs to be increased. Therefore, the virtual screening of bioactive compounds from natural products based on computational methods could be an interesting strategy. Among many sources of bioactive natural products, compounds from marine organisms, particularly microalgae and cyanobacteria, can be potential antiviral agents. The present study investigates bioactive antiviral compounds from microalgae and cyanobacteria as a potential inhibitor of SARS-CoV-2 by targeting Angiotensin-Converting Enzyme II (ACE2) using integrated

Indexed as

Bioactive compoundsMicroalgaeMolecular dockingMolecular dynamicsSARS-CoV-2Surface plasmon resonance

Identifiers

PMID36624782
PMCPMC9814374
OpenAlexW4313557131

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.