Evidence map›Paper›PMID 36624774›Full record

ArticleDialogues in health2023

Prevalence and factors associated with depression, anxiety, and stress symptoms among home isolated COVID-19 patients in Western Nepal.

Bikram Adhikari, Lisasha Poudel, Tek Bahadur Thapa, Deekshya Neupane, Pranita Maharjan, Ashley Hagaman, Niroj Bhandari, Nishan Katuwal, Bhawana Shrestha, Rashmi Maharjan and 8 more

Open access · goldAbstract read
In one paragraph

Article in Dialogues in health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 2 countries.

Bikram AdhikariResearch and Development Division, Dhulikhel Hospital, Kathmandu University Hospital, Dhulikhel, Nepal.
Lisasha PoudelResearch and Development Division, Dhulikhel Hospital, Kathmandu University Hospital, Dhulikhel, Nepal.
Tek Bahadur ThapaResearch and Development Division, Dhulikhel Hospital, Kathmandu University Hospital, Dhulikhel, Nepal.
Deekshya NeupaneResearch and Development Division, Dhulikhel Hospital, Kathmandu University Hospital, Dhulikhel, Nepal.
Pranita MaharjanResearch and Development Division, Dhulikhel Hospital, Kathmandu University Hospital, Dhulikhel, Nepal.
Ashley HagamanSocial and Behavioral Sciences Department, Yale School of Public Health, New Haven, USA.
Niroj BhandariResearch and Development Division, Dhulikhel Hospital, Kathmandu University Hospital, Dhulikhel, Nepal.
Nishan KatuwalResearch and Development Division, Dhulikhel Hospital, Kathmandu University Hospital, Dhulikhel, Nepal.
Bhawana ShresthaResearch and Development Division, Dhulikhel Hospital, Kathmandu University Hospital, Dhulikhel, Nepal.
Rashmi MaharjanResearch and Development Division, Dhulikhel Hospital, Kathmandu University Hospital, Dhulikhel, Nepal.
Sudip ShresthaDepartment of Community Programs, Dhulikhel Hospital-Kathmandu University Hospital, Dhulikhel, Nepal.
Akina ShresthaDepartment of Public Health, Kathmandu University School of Medical Sciences, Dhulikhel, Nepal.
Dipesh TamrakarResearch and Development Division, Dhulikhel Hospital, Kathmandu University Hospital, Dhulikhel, Nepal.
Bibek RajbhandariDepartment of Emergency Medicine and General Practice, Nepal police Hospital, Kathmandu, Nepal.
Brish Bahadur ShahiMinistry of Social Development, Karnali Province, Nepal.
Rajeev ShresthaResearch and Development Division, Dhulikhel Hospital, Kathmandu University Hospital, Dhulikhel, Nepal.
Biraj Man KarmacharyaResearch and Development Division, Dhulikhel Hospital, Kathmandu University Hospital, Dhulikhel, Nepal.
Archana ShresthaCenter for Methods in Implementation and Prevention Science, Yale School of Public Health, New Haven, CT, USA.
Dhulikhel Hospital · NPKathmandu University · NPYale University · USInstitute for Social and Environmental Research-Nepal · NP

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

Introduction: Globally, COVID-19 pandemic has a significant impact on mental health. In Nepal, COVID-19 positive cases have to self-isolate at home in multi-generational and multi-family households. This could be strongly associated with depression, anxiety, and stress-related health outcomes. Additionally, COVID-19 related stigma and fear of transmission may intensify depression, anxiety, and stress symptoms. This study determined the prevalence of depression, anxiety, and stress symptoms and their association with presence of COVID-19 symptoms and comorbid conditions among home isolated COVID-19 positives in the Karnali province, Nepal. Methods: We conducted a cross-sectional study to assess depression, anxiety, and stress symptoms among 402 home isolated COVID-19 patients of Karnali province from January to May 2021 using "Depression, Anxiety and Stress Scale-21 (DASS-21)". We interviewed patients to collect socio-demographic, DASS-21, COVID-19 symptoms, comorbid conditions, and self-treatment. We conducted a telephonic interview using a standardized questionnaire using Kobotoolbox. We calculated the prevalence of depression, anxiety, and stress symptoms. We utilized univariate and multivariate logistic regression to determine their association with the presence of COVID-19 symptoms and comorbid conditions. In multivariate logistic regression, we adjusted sociodemographic factors (age, gender, ethnicity, marital status, monthly family income, education level), smoking status and history of self-treatment. We reported adjusted odds ratios (aOR) with 95% confidence intervals. All analyses were conducted in R (version: 4.0.3). Results: The prevalence of depression, anxiety and stress symptoms among home isolated COVID-19 patients were 8.0% (95% CI: 5.5 to 11.1), 11.2% (95% CI: 8.3 to 14.7), and 4.0% (95% CI: 2.3 to 6.4) respectively. Higher odds of depression symptoms (aOR: 2.86; 95% CI: 1.10-7.44, Conclusion: Depression, anxiety, and stress symptoms were present in a significant proportion of home isolated COVID-19 patients in western Nepal and positively associated with the presence of COVID-19 symptoms. In this global COVID-19 pandemic, it is important to provide timely counseling to high-risk groups like those with comorbidities and COVID-19 symptoms to maintain a high level of mental health among home isolated COVID-19 patients.

Indexed as

Anxiety symptomsaOR, Adjusted Odds RatioCI, Confidence IntervalcOR, Crude Odds RatioCOVID-19DASS-21, Depression Anxiety and Stress Scale- 21Depression symptomsHome isolationMoSD, Ministry of Social DevelopmentNepalPCR, Polymerase Chain ReactionStress symptoms

Identifiers

PMID36624774
PMCPMC9721187
OpenAlexW4311090445

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.