Evidence map›Paper›PMID 36624761›Full record

ArticleData in brief2023

Data on common carotid artery occlusion inducing focalized stroke lesions after Pertussis toxin injection.

Veronika Leiss, Roland P Piekorz, Salvador Castaneda Vega, Christoph Jacoby, Ulrich Flögel, Katja Pexa, Jürgen Schrader, Bernd J Pichler, Sandra Beer-Hammer, Bernd Nürnberg

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Data in brief, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Veronika LeissDepartment of Pharmacology, Experimental Therapy and Toxicology, and Interfaculty Center for Pharmacogenomics and Drug Research, Eberhard Karls University Tübingen and University Clinic, Tübingen, Germany.
Roland P PiekorzInstitute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Salvador Castaneda VegaWerner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University Tübingen and University Clinic, Tübingen, Germany.
Christoph JacobyInstitute of Molecular Cardiology, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Ulrich FlögelInstitute of Molecular Cardiology, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Katja PexaInstitute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Jürgen SchraderInstitute of Molecular Cardiology, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Bernd J PichlerWerner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University Tübingen and University Clinic, Tübingen, Germany.
Sandra Beer-HammerDepartment of Pharmacology, Experimental Therapy and Toxicology, and Interfaculty Center for Pharmacogenomics and Drug Research, Eberhard Karls University Tübingen and University Clinic, Tübingen, Germany.
Bernd NürnbergDepartment of Pharmacology, Experimental Therapy and Toxicology, and Interfaculty Center for Pharmacogenomics and Drug Research, Eberhard Karls University Tübingen and University Clinic, Tübingen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This article contains raw and processed data related to research published by Vega et al. (2022). This complementary dataset provides further insight into the experimental validation of a single common carotid artery occlusion (CCAO) model upon pretreatment with pertussis toxin (PTX). We present data showing the extent of different PTX concentrations on neurological severity measured by Bederson score following CCAO. In addition, data indicate a protective effect of isoflurane on cerebral infarction and neurological deficits, as well as the consequences of PTX pretreatment on reperfusion after occlusion using time-of-flight magnetic resonance angiography. With these data, we aim to provide detailed experimental settings of this newly described model.

Indexed as

AngiographyCCAO, Common carotid artery occlusionGi proteinsischemic strokemurine modelPTX, Pertussis Toxin

Identifiers

PMID36624761
PMCPMC9823129

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.