Evidence map›Paper›PMID 36624694›Full record

ArticleEpidemiology and psychiatric sciences2023

Childhood adversities and risk of posttraumatic stress disorder and major depression following a motor vehicle collision in adulthood.

H N Ziobrowski, B Holt-Gosselin, M V Petukhova, A J King, S Lee, S L House, F L Beaudoin, X An, J S Stevens, D Zeng and 39 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Epidemiology and psychiatric sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.8field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

49 authors at 20 institutions in 2 countries.

H N ZiobrowskiDepartment of Health Care Policy, Harvard Medical School, Boston, MA, USA.
B Holt-GosselinDepartment of Psychology, Yale University, New Haven, CT, USA.
M V PetukhovaDepartment of Health Care Policy, Harvard Medical School, Boston, MA, USA.
A J KingDepartment of Health Care Policy, Harvard Medical School, Boston, MA, USA.
S LeeDepartment of Health Care Policy, Harvard Medical School, Boston, MA, USA.
S L HouseDepartment of Emergency Medicine, Washington University School of Medicine, St. Louis, MO, USA.
F L BeaudoinDepartment of Emergency Medicine & Department of Health Services, Policy, and Practice, The Alpert Medical School of Brown University, Rhode Island Hospital and The Miriam Hospital, Providence, RI, USA.
X AnDepartment of Anesthesiology, Institute for Trauma Recovery, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
J S StevensDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA.
D ZengDepartment of Biostatistics, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA.
T C NeylanDepartments of Psychiatry and Neurology, University of California San Francisco, San Francisco, CA, USA.
G D CliffordDepartment of Biomedical Informatics, Emory University School of Medicine, Atlanta, GA, USA.
S D LinnstaedtDepartment of Anesthesiology, Institute for Trauma Recovery, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
L T GermineInstitute for Technology in Psychiatry, McLean Hospital, Belmont, MA, USA.
K A BollenDepartment of Psychology and Neuroscience & Department of Sociology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
S L RauchInstitute for Technology in Psychiatry, McLean Hospital, Belmont, MA, USA.
J P HaranDepartment of Emergency Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA.
A B StorrowDepartment of Emergency Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
C LewandowskiDepartment of Emergency Medicine, Henry Ford Health System, Detroit, MI, USA.
P I MuseyDepartment of Emergency Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.
P L HendryDepartment of Emergency Medicine, University of Florida College of Medicine -Jacksonville, Jacksonville, FL, USA.
S SheikhDepartment of Emergency Medicine, University of Florida College of Medicine -Jacksonville, Jacksonville, FL, USA.
C W JonesDepartment of Emergency Medicine, Cooper Medical School of Rowan University, Camden, NJ, USA.
B E PunchesDepartment of Emergency Medicine, Ohio State University College of Medicine, Columbus, OH, USA.
M C KurzDepartment of Emergency Medicine, University of Alabama School of Medicine, Birmingham, AL, USA.
R A SworDepartment of Emergency Medicine, Oakland University William Beaumont School of Medicine, Rochester, MI, USA.
L A HudakDepartment of Emergency Medicine, Emory University School of Medicine, Atlanta, GA, USA.
J L PascualDepartment of Surgery, Department of Neurosurgery, University of Pennsylvania, Philadelphia, PA, USA.
M J SeamonPerelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
E HarrisDepartment of Emergency Medicine, Einstein Medical Center, Philadelphia, PA, USA.
C PearsonDepartment of Emergency Medicine, Wayne State University, Ascension St. John Hospital, Detroit, MI, USA.
R C MerchantDepartment of Emergency Medicine, Brigham and Women's Hospital, Boston, MA, USA.
R M DomeierDepartment of Emergency Medicine, Saint Joseph Mercy Hospital, Ypsilanti, MI, USA.
N K RathlevDepartment of Emergency Medicine, University of Massachusetts Medical School-Baystate, Springfield, MA, USA.
B J O'NeilDepartment of Emergency Medicine, Wayne State University, Detroit Receiving Hospital, Detroit, MI, USA.
P SergotDepartment of Emergency Medicine, McGovern Medical School at UTHealth, Houston, TX, USA.
L D SanchezDepartment of Emergency Medicine, Brigham and Women's Hospital, Boston, MA, USA.
S E BruceDepartment of Psychological Sciences, University of Missouri - St. Louis, St. Louis, MO, USA.
M W MillerNational Center for PTSD, Behavioral Science Division, VA Boston Healthcare System, Boston, MA, USA.
R H PietrzakNational Center for PTSD, Clinical Neurosciences Division, VA Connecticut Healthcare System, West Haven, CT, USA.
J JoormannDepartment of Psychology, Yale University, New Haven, CT, USA.
D M BarchDepartment of Psychological & Brain Sciences, Washington University in St. Louis, St. Louis, MO, USA.
D A PizzagalliDepartment of Psychiatry, Harvard Medical School, Boston, MA, USA.
S E HarteDepartment of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI, USA.
J M ElliottKolling Institute, University of Sydney, St Leonards, New South Wales, Australia.
K J ResslerDepartment of Psychiatry, Harvard Medical School, Boston, MA, USA.
S A McLeanDepartment of Emergency Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
K C KoenenDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, USA.
R C KesslerDepartment of Health Care Policy, Harvard Medical School, Boston, MA, USA.ORCID https://orcid.org/0000-0003-4831-2305
Harvard University · USUniversity of North Carolina at Chapel Hill · USYale University · USBrigham and Women's Hospital · USEmory University · USUniversity of Florida · USUniversity of Pennsylvania · USWashington University in St. Louis · USWayne State University · USBaystate Medical Center · USBoston University · USBrown University · USCooper Medical School of Rowan University · USEinstein Medical Center Philadelphia · USGeorgia Institute of Technology · USHenry Ford Health System · USIndiana University School of MedicineMercy Medical Center · USNorthwestern University · USOakland University · US

Funding

Longitudinal Assessment of Post-traumatic SyndromesU01MH110925 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KESSLER, RONALD C, KOENEN, KARESTAN C · 2016 to 2020
$25.8M
Early Life Stress and Depression: Molecular and Functional Imaging ApproachesR01MH095809 · NIMH · MCLEAN HOSPITAL · PI DU, FEI, PIZZAGALLI, DIEGO A · 2012 to 2024
$6.4M
NIMH NIH HHS R01 MH095809NIMH NIH HHS U01 MH110925NIMH NIH HHS U01MH110925
6 · The paper itself

Abstract

aimsChildhood adversities (CAs) predict heightened risks of posttraumatic stress disorder (PTSD) and major depressive episode (MDE) among people exposed to adult traumatic events. Identifying which CAs put individuals at greatest risk for these adverse posttraumatic neuropsychiatric sequelae (APNS) is important for targeting prevention interventions.

methodsData came from

resultsMost participants (90.9%) reported at least rarely having experienced some CA. Ever experiencing each CA other than emotional neglect was univariably associated with 3-month APNS (RRs = 1.31-1.60). Each CA frequency was also univariably associated with 3-month APNS (RRs = 1.65-2.45). In multivariable models, joint associations of CAs with 3-month APNS were additive, with frequency of emotional abuse (RR = 2.03; 95% CI = 1.43-2.87) and bullying (RR = 1.44; 95% CI = 0.99-2.10) being the strongest predictors. Control variable analyses found that these associations were largely explained by pre-MVC histories of PTSD and MDE.

conclusionsAlthough individuals who experience frequent emotional abuse and bullying in childhood have a heightened risk of experiencing APNS after an adult MVC, these associations are largely mediated by prior histories of PTSD and MDE.

Indexed as

Major Depressive DisorderStress Disorders, Post-TraumaticAdolescentAdultAgedDepressionHumansMiddle AgedMotor VehiclesSurveys and QuestionnairesYoung AdultDepressionmental healthpost traumatic stress disorderTrauma

Identifiers

PMID36624694
PMCPMC9879881
OpenAlexW4315435862

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.