ArticleAnimal microbiome2023
Age influences the temporal dynamics of microbiome and antimicrobial resistance genes among fecal bacteria in a cohort of production pigs.
Article in Animal microbiome, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 47 citations in OpenAlex.
- Age- and diet-driven assembly of the gut antibiotic resistome in humans and food-producing animals.Gut microbes · 2026Review
- Longitudinal investigation of the resistomes in Swedish pig farms.npj antimicrobials and resistance · 2026Article
- A Comprehensive Review of the Equine Gut Microbiome in Health and Disease.Veterinary sciences · 2026Review
- Antibiotic resistance genes in companion animals and humans driven by the gut microbial communities: composition, distribution, and implications.BMC veterinary research · 2026Article
- [Detection and Distribution Characteristics of Antibiotic Resistance Genes in Companion Animals].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026Article
- Weaning Influences Epithelial Morphology, Gene Expression and Gut Microbiota Composition in Piglets.Animals : an open access journal from MDPI · 2026Article
- Identification of gut microbiota features of diarrheic calves using the full-length 16S rRNA gene amplicon sequencing and machine learning.Animal microbiome · 2026Article
- Cross-sectional study characterizing the porcine faecal microbiome in commercial farms.Porcine health management · 2026Article
- Dynamic picture of the pig gut's microbiota under normal and pathological conditions.Animal microbiome · 2025Article
- Temporal dynamics of the resistome in gilts raised in an organic operation in which semen used for artificial insemination is the primary source of antimicrobial exposure.Scientific reports · 2025Article
- Impacts of different dietary soybean meal levels on jejunal immunity of nursery pigs at different days post-weaning.Journal of animal science and biotechnology · 2025Article
- Fecal microbiota transplantation in pigs: current status and future perspective.Animal microbiome · 2025Review
- The effect of dietary zinc on the microbiome and resistome of the gestating sow and neonatal piglets.Animal microbiome · 2025Article
- From mother to piglet: the lasting influence of the maternal microbiome.Animal microbiome · 2025Article
- Characterization of microbiota signatures in Iberian pig strains using machine learning algorithms.Animal microbiome · 2025Article
- Influence of selected dosages of plastic microparticles on the porcine fecal microbiome.Scientific reports · 2025Article
- Antimicrobial resistance genes in weaned pigs: quantitative abundance and group dynamics assessed by qPCR.Frontiers in veterinary science · 2025Article
- Performance and Health Parameters of Sows and Their Litters Using a Probiotic Supplement Composed ofAnimals : an open access journal from MDPI · 2024Article
- Antimicrobial resistance among indicator Enterococcus faecium and Escherichia coli in Swedish pig farms.Acta veterinaria Scandinavica · 2024Article
- Dispersion of antimicrobial resistant bacteria in pig farms and in the surrounding environment.Animal microbiome · 2024Article
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe pig gastrointestinal tract hosts a diverse microbiome, which can serve to select and maintain a reservoir of antimicrobial resistance genes (ARG). Studies suggest that the types and quantities of antimicrobial resistance (AMR) in fecal bacteria change as the animal host ages, yet the temporal dynamics of AMR within communities of bacteria in pigs during a full production cycle remains largely unstudied.
resultsA longitudinal study was performed to evaluate the dynamics of fecal microbiome and AMR in a cohort of pigs during a production cycle; from birth to market age. Our data showed that piglet fecal microbial communities assemble rapidly after birth and become more diverse with age. Individual piglet fecal microbiomes progressed along similar trajectories with age-specific community types/enterotypes and showed a clear shift from E. coli/Shigella-, Fusobacteria-, Bacteroides-dominant enterotypes to Prevotella-, Megaspheara-, and Lactobacillus-dominated enterotypes with aging. Even when the fecal microbiome was the least diverse, the richness of ARGs, quantities of AMR gene copies, and counts of AMR fecal bacteria were highest in piglets at 2 days of age; subsequently, these declined over time, likely due to age-related competitive changes in the underlying microbiome. ARGs conferring resistance to metals and multi-compound/biocides were detected predominately at the earliest sampled ages.
conclusionsThe fecal microbiome and resistome-along with evaluated descriptors of phenotypic antimicrobial susceptibility of fecal bacteria-among a cohort of pigs, demonstrated opposing trajectories in diversity primarily driven by the aging of pigs.
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Registered trials
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