Evidence map›Paper›PMID 36624532›Full record

SynthesisJournal of orthopaedic surgery and research2023

The incidence and risk factors for femoral head necrosis after femoral neck fracture in pediatric patients: a systematic review and meta-analysis.

Pengfei Xin, Ziqi Li, Shaoqiang Pei, Qi Shi, Lianbo Xiao

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Journal of orthopaedic surgery and research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 3 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
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  4. Article
  5. Article
  6. Follow-up After Proximal Femur Fracture Fixation-We Need to Do Better.Journal of the Pediatric Orthopaedic Society of North America · 2025
    Article
  7. Article
  8. Risk factors of avascular femoral head necrosis after a pediatric femoral neck fracture: a 15-year follow up and an adjustment to the Delbet classification.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Pengfei Xin *Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Ziqi Li *The Third Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou, China.
Shaoqiang PeiShanghai University of Traditional Chinese Medicine, Shanghai, China.
Qi ShiShanghai University of Traditional Chinese Medicine, Shanghai, China. shiqi@shutcm.edu.cn.
Lianbo XiaoArthritis Research Institute of Integrated Traditional Chinese and Western Medicine, Shanghai Academy of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China. xiao_lianbo@163.com.
Shanghai University of Traditional Chinese Medicine · CNThe Third Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine · CN

Funding

Shanghai 13th Five-Year Key Specialized College-Department of Osteoarthritis and Arthritis of Integrated Traditional Chinese and Western Medicine shslczdzk04801The construction of key areas of clinical highland of traditional Chinese medicine in Shanghai (ZY(2021-2023)-0201-06) ZY(2021-2023)-0201-06the project of Shanghai Nature Fund 22ZR1453100
6 · The paper itself

Abstract

backgroundThe incidence of avascular necrosis (AVN) after pediatric femoral neck fracture (PFNF) in the literature varies widely, and the risk factors associated with AVN after PFNF are controversial. Therefore, this study aimed to accurately investigate the incidence of AVN after PFNF and systematically evaluate and meta-classify their risk factors.

methodsA comprehensive search was performed of PubMed, Web of Science, and Embase. The pooled rate and 95% confidence interval (CI) were used to assess the incidence of AVN after PFNF, and pooled odds ratio (OR) were calculated to measure the effect sizes. In addition, we performed subgroup, stratified, and publication bias analyses.

resultsA total of 30 articles were included in our meta-analysis, with 303 AVN cases among 1185 patients. The pooled incidence of AVN after PFNF was 22% (95% CI 18%, 27%). Subgroup analyses indicated Delbet type I-IV fracture incidences with AVN of 45%, 32%, 17%, and 12%, respectively. The incidence of AVN after PFNF in Asia was 19%, lower than in Africa at 36%, Europe at 26%, and North America at 23%. In addition, the larger sample size group and the earlier published literature group showed a higher incidence of necrosis. Stratified analyses showed that patient age and Delbet fracture classification were both important factors affecting AVN after PFNF (OR = 1.61, p = 0.02 and OR = 3.02, p < 0.001, respectively), while the time to treatment was not (OR = 0.9, p = 0.71).

conclusionThe pooled incidence of AVN after PFNF was ~ 22%; furthermore, the available evidence demonstrates that patient age and Delbet type of fracture were important influencing factors of AVN after PFNF.

Indexed as

Femoral Neck FracturesFemur Head NecrosisChildEuropeHumansIncidenceRisk FactorsFemoral head necrosisFemoral neck fractureIncidenceMeta-analysisPediatricRisk factors

Identifiers

PMID36624532
PMCPMC9830722
OpenAlexW4313888531

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.