ArticleVirology journal2023
The changed endemic pattern of human adenovirus from species B to C among pediatric patients under the pressure of non-pharmaceutical interventions against COVID-19 in Beijing, China.
Article in Virology journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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18 citing papers in PubMed, 21 citations in OpenAlex.
- Drug combination treatment as a strategy for inhibiting human adenovirus replication.Antiviral research · 2026Article
- Adenovirus Genotypes Associated With Severe Acute Respiratory Infections Outbreak in Children, in Antioquia, Colombia, 2022-2023.The Pediatric infectious disease journal · 2026Article
- The changed endemic pattern of human adenovirus from species C to B among children in 2022-2024 in Shenzhen, China.Scientific reports · 2026Article
- Dynamic Shifts in Respiratory Pathogens During the First Post-COVID-19 Autumn-Winter in Beijing.International journal of general medicine · 2026Article
- Genomic characterization and evolutionary dynamics of human adenovirus C (HAdV-C) in Beijing (2023-2024): insights into multiple recombination and adaptive evolution.Virus evolution · 2026Article
- Risk factors for hospitalization in pediatric patients with human adenovirus infection and changes in epidemiological and clinical characteristics before and after the COVID-19 pandemic in China: a multicenter retrospective study.Frontiers in cellular and infection microbiology · 2026Article
- Epidemiology of Respiratory Adenovirus Infections Among Hospitalized Children in Hainan Province, China, 2021-2024.Pathogens (Basel, Switzerland) · 2025Article
- Long-Term Epidemiological Trends of Human Adenovirus Infection in South Korea: A Single-Center Study (2007-2024).Pathogens (Basel, Switzerland) · 2025Article
- Molecular characteristics of human adenovirus isolated from the 2024 influenza-like illness outbreaks in Suzhou City, China.Virology journal · 2025Article
- Epidemiological characteristics of human adenovirus infections in China, 2020-2023.Biosafety and health · 2025Article
- Comparative analysis between genotypes of adenovirus isolates from hospitalized children with acute respiratory tract infections and clinical manifestations in Wuhan, China, from June 2022 to September 2023.Virologica Sinica · 2025Article
- First identification of human adenovirus subtype 21a in Shenzhen, China with high-throughput sequencing.Frontiers in microbiology · 2025Article
- Epidemiological characteristics and genomic analysis of respiratory adenovirus in Lanzhou City from 2023 to 2025.Frontiers in cellular and infection microbiology · 2025Article
- Mutated Adenovirus Attacks in West Bengal, India: Risk Evaluation of Multi-Country Outbreaks and Mitigation Strategies.Nursing open · 2024Review
- Molecular characterization of human adenoviruses associated with pediatric respiratory infections in Karachi, Pakistan.BMC infectious diseases · 2024Article
- Inhibition, transition, and surge: dynamic evolution of pediatric respiratory pathogen trends amid COVID-19 pandemic policy adjustments.Frontiers in public health · 2024Article
- Current status and reflections on the diagnosis and treatment of respiratory tract infections in children in the COVID-19 pandemic and post-COVID-19 era.Pediatric discovery · 2023Review
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Authors and funding
13 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundUnder the pressure of non-pharmaceutical interventions (NPIs) targeting severe acute respiratory syndrome coronavirus 2, the prevalence of human adenovirus (HAdV) was monitored before and after NPIs launched on Jan 24, 2020 in pediatric patients in Beijing, China.
methodsRespiratory samples collected from children hospitalized with acute respiratory infections from Jan 2015 to Dec 2021 were screened by direct immunofluorescence test or capillary electrophoresis-based multiplex PCR assay. The hexon, penton base, and fiber genes were amplified from HAdV positive specimens, then sequenced. For HAdV typing, phylogenetic trees were built by MEGA X. Then clinical data of HAdV positive cases were collected. All data were evaluated using SPSS Statistics 22.0 software.
resultsA total of 16,097 children were enrolled and 466 (2.89%, 466/16,097) were HAdV-positive. The positive rates of HAdV varied, ranging from 4.39% (151/3,438) in 2018 to1.25% (26/2,081) in 2021, dropped from 3.19% (428/13,408) to 1.41% (38/2,689) from before to after NPIs launched (P < 0.001). There were 350 cases typed into nine types of species B, C, or E and 34 recorded as undetermined. Among them, HAdV-B3 (51.56%, 198/384) was the most prevalent types from 2015 to 2017, and HAdV-B7 (29.17%, 112/384) co-circulated with HAdV-B3 from 2018 to 2019. After NPIs launched, HAdV-B3 and B7 decreased sharply with HAdV-B7 undetected in 2021, while HAdV-C1 became the dominant one and the undetermined were more.
conclusionsThe endemic pattern of HAdV changed in Beijing because of the NPIs launched for COVID-19. Especially, the dominant types changed from HAdV-B to HAdV-C.
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