ArticleWorld journal of surgical oncology2023
The diagnostic accuracy of 332 incisional biopsies in patients with malignant tumors in the musculoskeletal system.
Article in World journal of surgical oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Performance of deep learning-based segmentation of soft tissue sarcoma by MRI sequence, tumor type and location.Skeletal radiology · 2026Article
- A Predictive MRI Radiomics Model for Histologic Differentiation in Soft Tissue Sarcomas.Cancers · 2026Article
- Improving MRI-based differentiation of brain metastasis, glioblastoma, and primary CNS lymphoma using deep learning.Neuroradiology · 2026Article
- Article
- First Experiences with Fusion of PET-CT and MRI Datasets for Navigation-Assisted Percutaneous Biopsies for Primary and Metastatic Bone Tumors.Diagnostics (Basel, Switzerland) · 2024Article
- Not every knee tumour is a ganglion - retrospective analysis of benign and malign tumour entities around the knee.Archives of orthopaedic and trauma surgery · 2024Article
- Lymphadenectomy in the treatment of sarcomas - indications and technique.Oncology reviews · 2024Review
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Authors and funding
8 authors.
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Abstract
backgroundIt is known that specimen collection followed by histopathological workup is the core of evidence-based medical therapy of musculoskeletal tumors. There exist many controversies about how a biopsy should be performed. While some centers recommend minimal invasive biopsy procedures, mostly the core needle biopsy (CNB), others prefer the incisional biopsy. PURPOSE OF THE STUDY: This study aimed to determine the accuracy of incisional biopsy for malignant tumors in the musculoskeletal system. Moreover, advantages and disadvantages to other biopsy methods are discussed.
methodsThis retrospective, single-center study about 844 incisional biopsies (benign and malignant) analysis the diagnostic accuracy of 332 malignant tumors, concerning the final histopathological result. In addition, surgical complications are analyzed to find the best way to plan and treat patients timely and correct. Secondary endpoints are the patients age, the pure operation time, as well as the type of tumor, and the subsequent therapy.
resultsIn summary, incisional biopsy corresponded a sensitivity of 100% for malignancy in 844 incisional biopsies and a specificity of 97.6% in 332 malignant tumors, but it features greater operative expense (incision/suture 23.5 min) and the risk of general anesthesia.
conclusionThe method of biopsy should be tailored to the individual patient and the experience of the center performing the procedure.
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