ArticleBMC pregnancy and childbirth2023
Pregnancy outcomes in women with pulmonary hypertension: a retrospective study in China.
Article in BMC pregnancy and childbirth, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 12 citations in OpenAlex.
- Single Atrium Repair with Delayed Sternal Closure in a Postpartum Multiparous Woman: A Case Report.Journal of clinical medicine · 2026Article
- [Perioperative outcomes and anesthetic management of pregnancy termination in patients with pulmonary hypertension].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2026Article
- Maternal and fetal outcomes in patients with congenital heart disease associated with pulmonary arterial hypertension in high-altitude areas: a retrospective cohort study.BMC pregnancy and childbirth · 2026Article
- Extracorporeal membrane oxygenation for pulmonary arterial hypertension complicating pregnancy: case series and literature review.BMC pregnancy and childbirth · 2026Review
- Risk stratification and multidisciplinary management strategies for pregnancy complicated by pulmonary arterial hypertension: a narrative review.Frontiers in endocrinology · 2026Review
- Maternal and neonatal outcomes in pregnancies complicated with pulmonary hypertension: a retrospective cohort study.European journal of medical research · 2025Article
- Pregnancy in patients with pulmonary hypertension: a systematic review and meta-analysis with meta-regression.Journal of thoracic disease · 2025Article
- Analysis of Clinical Characteristics of 54 Dead Pregnant Patients With Pulmonary Hypertension.Pulmonary circulation · 2025Article
- Pulmonary Hypertension in Women.Methodist DeBakey cardiovascular journal · 2024Review
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn recent years, with the development of monitoring conditions and the application of pulmonary vascular-targeted drugs, pregnancy outcomes in women with pulmonary hypertension (PH) have improved, but the maternal mortality rate is still high. The purpose of this study was to describe the maternal-foetal outcomes in pregnant women with PH.
methodsThe clinical data of 154 pregnant women with PH who were admitted to the Third Affiliated Hospital of Guangzhou Medical University from January 2011 to December 2020 were collected and descriptively analysed.
resultsAmong the 154 pregnant women with PH, 6 (3.9%) had idiopathic pulmonary arterial hypertension (iPAH), 41 (26.6%) had pulmonary arterial hypertension (PAH) associated with congenital heart disease (CHD-PAH), 45 (29.2%) had PAH related to other diseases (oPAH), and 62 (40.3%) had PH related to left heart disease (LHD-PH). The systolic pulmonary artery pressure (sPAP) was 36-49 mmHg in 53.2% of the patients, 50-69 mmHg in 22.1% of the patients and ≥ 70 mmHg in 24.7% of the patients. Five (3.2%) pregnant women died within 1 week after delivery; iPAH patients had the highest mortality rate (3/6, 50%). Fifty-four patients (35.1%) were admitted to the intensive care unit (ICU), and the incidence of heart failure during pregnancy was 14.9%. A total of 70.1% of the patients underwent caesarean section; 42.9% had premature infants; 28.6% had low-birth-weight (LBW) infants; 13.0% had very-low-birth-weight (VLBW) infants; 3.2% had extremely-low-birth-weight (ELBW) infants; 61% had small for gestational age (SGA) infants; and 1.9% experienced neonatal mortality.
conclusionThere were significant differences in the maternal-foetal outcomes in the iPAH, CHD-PAH, oPAH and LHD-PH groups. Maternal mortality was highest in the iPAH group; therefore, iPAH patients should be advised to prevent pregnancy. Standardized and multidiscipline-assisted maternal management is the key to improving maternal-foetal outcomes.
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