Evidence map›Paper›PMID 36624365›Full record

ArticleBMC medical research methodology2023

Studies with statistically significant effect estimates are more frequently published compared to non-significant estimates in oral health journals.

Jadbinder Seehra, Hadil Khraishi, Nikolaos Pandis

Abstract read
In one paragraph

Article in BMC medical research methodology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jadbinder SeehraCentre for Craniofacial Development & Regeneration, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, Guy's Hospital, Guy's and St Thomas NHS Foundation Trust, Floor 25, SE1 9RT, London, UK.
Hadil KhraishiOral & Maxillofacial Surgery and Orthodontics Clinic, Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge, CB2 0QQ, UK.
Nikolaos PandisDepartment of Orthodontics and Dentofacial Orthopedics, Dental School/Medical Faculty, University of Bern, Freiburgstrasse 7, CH-3010, Bern, Switzerland. npandis@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStudies reporting statistically significant effect estimates tend to be more frequently published compared to studies reporting non-significant or equivalent estimates. Consequently, this may lead to distortion of the literature. The aim of this study is to assess the prevalence of reporting statistically significant effect estimates in leading oral health journals and to explore associations between the effect estimates and record characteristics.

methodsAn electronic database search was undertaken of a selection of leading oral health journals including general oral health journals to identify primary oral health records published in 2019. Descriptive statistics and population average GEE logistic regression model was used to assess associations between articles reporting a statistically significant effect estimate and the record characteristics.

resultsIn 1335 records, 82.4% records reported a statistically significant effect estimate. All speciality journals compared to general oral health journals were less likely to publish a record with significant effect estimates. Authors based in Asia or other (OR 1.49; 95% CI :1.02,2.19; p = 0.037) were more likely to report significant effect estimates compared to those based in Europe. Interventional (OR 0.35; 0.22,0.58; p < 0.001) and observational (OR 0.56; 0.36, 0.89; p = 0.013) records were less likely to report significant effect estimates compared to in-vitro studies. Registered records were less likely to report significant effect estimates when compared to non-registered studies (OR 0.22; 95% CI :0.14,0.32; p < 0.001).

conclusionThe publishing of records with significant effect estimates is prevalent within the oral health literature. To reduce dissemination bias and overestimation of effect sizes in systematic reviews, the publishing of studies with non-significant or equivalent effect estimates should be encouraged.

Indexed as

Oral HealthPeriodicals as TopicHumansPublication BiasPublicationsSystematic Reviews as TopicOral healthPublication biasPublishing trendsSelective reportingSignificance biasSpeciality

Identifiers

PMID36624365
PMCPMC9827647

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.